Markers |
Haplotype |
Related Gene(s)/Region(s) |
Overlap with SZ |
Statistical Results |
Description |
Result Category |
Reference |
|
rs2439300 - rs2439286 - rs10095694 - rs2919390 |
|
NRG1
|
|
rs2439305 - rs2439300 - rs2439286 - rs10095694 |
|
NRG1
|
|
rs2919390 - rs6988339 |
|
NRG1
|
|
rs2919390 - rs6988339 - rs3757930 |
|
NRG1
|
P-value = 0.0001 fo......
P-value = 0.0001 for SZ, P-value = 0.0001 for SCZ and BP
More...
|
the most significan......
the most significant haplotype in SCZ was also nominally significant in the BP sample; this was the only haplotype to withstand permutation analysis in this study, identifying a new region of association with both schizophrenia and the combined case group in the Scottish population
More...
|
Positive |
Thomson, P. A., 2007 |
|
rs2919390 - rs6988339 - rs3757930 - rs10103750 |
|
NRG1
|
|
(HTR4_SVRSNP1) - (HTR4_SVRSNP4) |
C-G |
HTR4
|
Haplotype analysis:......
Haplotype analysis:Transmission disequilibrium test:Schizophrenia(RIKEN families):T/NT=19/18, chi square=0.03, P-value = 0.87
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Ohtsuki, T.,2002 |
|
rs553950 - rs327329 - rs7007662 |
|
NRG1
|
|
rs553950 - rs327329 - rs7007662 - rs1481762 |
|
NRG1
|
|
D4S2281 - D4S1506 |
|
4p16.1
|
Two-marker associat......
Two-marker association:P-value = 0.0009
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Als, T. D.,2004 |
|
rs6988339 - rs3757930 |
|
NRG1
|
|
D4S2923 - D4S2928 - D4S1582 |
|
4p16.1
|
Three-marker associ......
Three-marker association:P-value = 0.0005
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Als, T. D.,2004 |
|
rs6988339 - rs3757930 - rs10103750 |
|
NRG1
|
|
D4S394 - D4S2983 |
|
4p16.1
|
Two-marker associat......
Two-marker association:P-value = 0.0320
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Als, T. D.,2004 |
|
rs6988339 - rs3757930 - rs10103750 - rs10503932 |
|
NRG1
|
|
D4S403 - D4S3048 |
|
4p16.1
|
Two-marker associat......
Two-marker association:P-value = 0.0101
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Als, T. D.,2004 |
|
MDAAO4 - MDAAO5 - MDAAO6 |
A-C-G |
DAO
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.042, individual P-value = 0.045, OR=1.29
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
MDAAO4 - MDAAO5 - MDAAO6 |
A-C-T |
DAO
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.042, individual P-value = 0.903, OR=1
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
MDAAO4 - MDAAO5 - MDAAO6 |
C-C-G |
DAO
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.042, individual P-value = 0.57, OR=1.18
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
MDAAO4 - MDAAO5 - MDAAO6 |
C-T-T |
DAO
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.042, individual P-value = 0.019, OR=0.72
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
M12 - M15 - M23 - M24 |
T-A-C-T |
DAOA
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.032, individual P-value = 0.7, OR=1.07
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
M12 - M15 - M23 - M24 |
T-A-T-A |
DAOA
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.032, individual P-value = 0.093, OR=1.31
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
M12 - M15 - M23 - M24 |
C-G-C-T |
DAOA
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.032, individual P-value = 0.07, OR=1.29
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
rs7452939 - rs6903874 - rs6937506 |
|
TAAR6
|
Global X<sup>......
Global X<sup>2</sup>=18.49, df=3, P-value = 0.00042
More...
|
There were signific......
There were significant global differences in haplotype frequency between schizophrenia patients compared to controls.
More...
|
Positive |
Pae, C. U., 2008 |
|
M12 - M15 - M23 - M24 |
C-G-T-A |
DAOA
|
Haplotype analysis:......
Haplotype analysis:allele, global P-value = 0.032, individual P-value = 0.00023, OR=0.57
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Schumacher, J.,2004 |
|
rs7452939 - rs6903874 - rs6937506 |
GCT |
TAAR6
|
X<sup>2</s......
X<sup>2</sup>=12.87, df=1, P-value = 0.0003
More...
|
The GCT haplotype w......
The GCT haplotype was significantly over-represented in the patients with schizophrenia compared to controls.
More...
|
Positive |
Pae, C. U., 2008 |
|
rs16944 - (IL1RN_intron 2_VNTR) |
C-VNTR(A2) |
IL1B
IL1RN
|
Haplotype analysis:......
Haplotype analysis:Schizophrenia v controls: chi square= 12.70, global P-value = 0.012; chi square= 9.99, individual P-value = 0.0015; OR = 2.49(95% CI: 1.33 to 4.64).
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Papiol, S.,2004 |
|
rs646558 - rs2303377 |
C-T, C-(T/C), (C/A)-(T/C) |
NCAM1
|
C-T, C-(T/C), (C/A)......
C-T, C-(T/C), (C/A)-(T/C); chi-square P-value = <0.0001, X<sup>2</sup>=28.04, d.f.=3; chi-square P-value = <0.0001, X<sup>2</sup>=27.90, d.f.=2 for BD and SZ
More...
|
Three of the two ma......
Three of the two marker haplotypes for rs646558 and rs2303377 showed varying frequencies between schizophrenia and controls.
More...
|
Positive |
Atz, M. E., 2007 |
|
rs737865 - rs165599 |
G-G |
COMT
|
OR (95% CI)=1.27 (1......
OR (95% CI)=1.27 (1.08-1.50) of males, OR (95% CI)=1.51 (1.20-1.90) of females
More...
|
previously found to......
previously found to be associated with schizophrenia
More...
|
Positive |
Shifman, S., 2004 |
|
rs363387 - rs363343 - rs363272 |
T-A-G |
SLC18A2
|
OR=3.817 (95%CI: 1.......
OR=3.817 (95%CI: 1.60-9.09) in SZ cases; OR=4.1 (95%CI: 1.83-9.21) in SZ and BD combined group; Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group
More...
|
The estimation of h......
The estimation of haplotype effects using the UNPHASED software showed an increased risk, compared to controls, for both bipolar disorder and/or schizophrenia in carriers of TAG haplotype
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs737865 - rs165688 - rs165599 |
G-G-G |
COMT
|
OR (95% CI)=1.36 (1......
OR (95% CI)=1.36 (1.15-1.61) of males, OR (95% CI)=1.57 (1.25-1.98) of females
More...
|
previously found to......
previously found to be associated with schizophrenia
More...
|
Positive |
Shifman, S., 2004 |
|
rs363387 - rs363343 - rs363272 |
C-C-A |
SLC18A2
|
OR=2.775 (95%CI: 0.......
OR=2.775 (95%CI: 0.98-7.85) in SZ cases; OR=2.336 (95%CI: 1.28-4.26) in SZ and BD combined group; Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group
More...
|
a trend association......
a trend association was also found for CCA combination in SZ cases, which reached significance when patients with bipolar disorder and schizophrenia were grouped together
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363387 - rs363343 - rs363272 |
T-C-A |
SLC18A2
|
Likelihood ratio c......
Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group
More...
|
significantly more ......
significantly more common among controls compared to patients' groups
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363387 - rs363343 - rs363272 |
C-A-G |
SLC18A2
|
Likelihood ratio c......
Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group
More...
|
significantly more ......
significantly more common among controls compared to patients' groups
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363387 - rs363420 - rs363272 |
|
SLC18A2
|
Global P-value <......
Global P-value < E-04
More...
|
yielded globally si......
yielded globally significant evidence for association in SZ cases, and BD and SZ combined group
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363387 - rs363420 - rs363343 |
|
SLC18A2
|
Global P-value <......
Global P-value < E-04
More...
|
yielded globally si......
yielded globally significant evidence for association in SZ cases, and BD and SZ combined group
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363387 - rs363420 - rs363343 - rs363272 |
|
SLC18A2
|
Global P-value <......
Global P-value < E-06
More...
|
The result revealed......
The result revealed highly significant differences in haplotype distributions between schizophrenic patients and between BD and SZ combined group and controls
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363420 - rs363272 |
|
SLC18A2
|
Global P-value <......
Global P-value < 0.0001 in SZ cases; Global P-value < E-06 in BD and SZ combined group
More...
|
the 2-marker haplot......
the 2-marker haplotype yielded globally significant evidence for association in SZ cases and BD and SZ combined group
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363420 - rs363343 |
|
SLC18A2
|
Global P-value <......
Global P-value < E-06
More...
|
the 2-marker haplot......
the 2-marker haplotype yielded globally significant evidence for association in SZ cases and BD and SZ combined group
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs363420 - rs363343 - rs363272 |
|
SLC18A2
|
Global P-value <......
Global P-value < E-04
More...
|
yielded globally si......
yielded globally significant evidence for association in SZ cases, and BD and SZ combined group
More...
|
Positive |
Gutierrez, B., 2007 |
|
rs6265 - microsatellite (GT)n |
A-(GT1) |
BDNF
|
For SZ, X<sup>......
For SZ, X<sup>2</sup>=29.85; P-value < 4.65E-08 (P<4.65E-07 after Bonferroni correction); OR=0.30; upper 95% CI=0.46; lower CI=-0.77
More...
|
Association was obs......
Association was observed in SZ.
More...
|
Positive |
Neves-Pereira, M.,2005 |
|
rs6265 - microsatellite (GT)n |
G-(GT1) |
BDNF
|
For SZ, X<sup>......
For SZ, X<sup>2</sup>=8.38; P-value = 0.0038 (P=0.04 after Bonferroni correction); OR=2.18; upper 95% CI=3.71; lower CI=1.31.
More...
|
Association was obs......
Association was observed in SZ.
More...
|
Positive |
Neves-Pereira, M.,2005 |
|
rs1538977 - rs2492367 - rs2812393 |
T-T-G |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.039(all), 0.48(male), 0.1(female); individual P-value = 0.0062(all)
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
rs1538977 - rs2492367 - rs2812393 - rs1322784 |
T-T-G-T |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.0056(all), 0.84(male), 0.032(female); individual P-value = 0.0075(all)
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
rs1954175 - rs1538977 - rs2492367 - rs2812393 |
A-C-C-G |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, individual P-value = 0.00048(male)
More...
|
Significant associa......
Significant association was found in individual P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
478B14-848 - 420M9-1395 - SNP8NRG221533 |
5-7-2 |
NRG1
|
Haplotype analysis:......
Haplotype analysis:FBAT, Global X<sup>2</sup>= 13.949, 3df, P = 0.003; individual P-value = 0.739015
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Voineskos, D.,2009 |
|
rs1954175 - rs1538977 - rs2492367 - rs2812393 |
G-T-T-G |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.0064(all), 0.0046(male), 0.31(female); individual P-value = 0.005(all)
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
478B14-848 - 420M9-1395 - SNP8NRG221533 |
6-4-1 |
NRG1
|
Haplotype analysis:......
Haplotype analysis:FBAT, Global X<sup>2</sup>= 13.949, 3df, P = 0.003; individual P-value = 0.000581
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Voineskos, D.,2009 |
|
rs2492367 - rs2812393 - rs1322784 |
C-C-C |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.0079(all), 0.32(male), 0.021(female); individual P-value = 0.0044(all)
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
478B14-848 - 420M9-1395 - SNP8NRG221533 |
6-4-2 |
NRG1
|
Haplotype analysis:......
Haplotype analysis:FBAT, Global X<sup>2</sup>= 13.949, 3df, P = 0.003; individual P-value = 0.155978
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Voineskos, D.,2009 |
|
rs2492367 - rs2812393 - rs1322784 - rs2759346 |
|
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.043(all), 0.24(male), 0.0074(female);
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
rs2812393 - rs1322784 |
C-C |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.0044(all), 0.21(male), 0.018(female); individual P-value = 0.0036(all)
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Thomson, P. A.,2005(a) |
|
rs10939038 - rs3756207 |
|
PI4K2B
|
haplotype analysis:......
haplotype analysis:global P-value = 0.005, permuted global P-value = 0.039, SE:0.006 in the schizophrenia sample
More...
|
Schizophrenia showe......
Schizophrenia showed association with a two-marker haplotype in schizophrenia but not bipolar disorder.
More...
|
Positive |
Houlihan, L.M.,2009 |
|
rs17408391 - rs10939038 |
|
PI4K2B
|
haplotype analysis:......
haplotype analysis:global P-value = 0.005, permuted global P-value = 0.039, SE:0.006 in the schizophrenia sample
More...
|
Schizophrenia showe......
Schizophrenia showed association with a two-marker haplotype in schizophrenia but not bipolar disorder.
More...
|
Positive |
Houlihan, L.M.,2009 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-166bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.134
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-168bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.232
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-170bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.944
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138820 - rs4468 |
CC |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.0027 calculated using PLINK.
More...
|
'Risk'' haplotypes ......
'Risk'' haplotypes over-represented among patients with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-172bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.821
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138820 - rs4468 |
TT |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.041 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-174bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.0033
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138820 - rs4468 - rs138841 |
CCA |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.0074 calculated using PLINK.
More...
|
'Risk'' haplotypes ......
'Risk'' haplotypes over-represented among patients with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-170bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.037
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138820 - rs4468 - rs138841 |
TTC |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.044 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-174bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.0024
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138841 - rs138855 |
CG |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.017 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-174bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.067
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138841 - rs138855 - rs138864 |
CGG |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.0081 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-176bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for Schizophrenia, global P-value = 0.016, Bonferroni-Corrected P-value = 0.192, individual P-value = 0.627
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive |
Schumacher, J.,2005 |
|
rs138864 - rs2239848 |
GG |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.048 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs4468 rs138841 |
CA |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.0073 calculated using PLINK.
More...
|
'Risk'' haplotypes ......
'Risk'' haplotypes over-represented among patients with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs4468 rs138841 |
TC |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.043 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs4468 - rs138841 - rs138855 |
TCG |
BRD1
|
Empirical haplotype......
Empirical haplotype-specific P-value = 0.042 calculated using PLINK.
More...
|
'Protective'' haplo......
'Protective'' haplotypes over-represented among controls with SZ
More...
|
Positive |
Nyegaard, M., 2010 |
|
rs1130233 - rs3730358 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0247
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs1130233 - rs3730358 - rs1130214 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0021
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs1130233 - rs3730358 - rs1130214 - rs3803300 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0018
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs2494732 - rs1130233 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0394
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs2494732 - rs1130233 - rs3730358 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0147
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs2494732 - rs1130233 - rs3730358 - rs1130214 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.000211
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs2494732 - rs1130233 - rs3730358 - rs1130214 - rs3803300 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.000593
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs11736084 - rs1282 - rs17844778 - rs9685931 |
T-C-C-G |
GPR78
|
Global test P-value......
Global test P-value (permuted P-value, s.e.)=0.015 (0.044, 0.002), Individual test P-value (permuted P-value, s.e.)=0.003 (0.048, 0.002), OR (95% CI)=0.547 (0.367-0.815) in all female affected
More...
|
No haplotype tested......
No haplotype tested by either the global or individual test maintained its significance after permutation analysis. However, the global test P-values of two related haplotypes remained significant in both the BPAD females and all affected females.
More...
|
Positive |
Underwood, S. L., 2006 |
|
rs11736084 - rs1282 - rs17844778 - rs9685931 - rs9799720 |
T-C-C-G-C |
GPR78
|
Global test P-value......
Global test P-value (permuted P-value, s.e.)=0.017 (0.033, 0.002), Individual test P-value (permuted P-value, s.e.)=0.004 (0.070, 0.003), OR (95% CI)=0.562 (0.375-0.842) in all female affected
More...
|
No haplotype tested......
No haplotype tested by either the global or individual test maintained its significance after permutation analysis. However, the global test P-values of two related haplotypes remained significant in both the BPAD females and all affected females.
More...
|
Positive |
Underwood, S. L., 2006 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
T-C-C |
GRIN2B
|
P-value = 0.97519, ......
P-value = 0.97519, Z=-0.031 in schizophrenia family sample; P-value = 0.01 in schizophrenia case-controls sample
More...
|
Haplotype analyses ......
Haplotype analyses on the schizophrenia case-control sample also showed significant elevation in the frequency of haplotype G-C-T in schizophrenia, and T-C-C in controls. The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Positive |
Martucci, L., 2006 |
|
rs2498804 - rs2494732 - rs1130233 - rs3730358 - rs1130214 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0048
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs2498804 - rs2494732 - rs1130233 - rs3730358 - rs1130214 - rs3803300 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0026
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs3730358 - rs1130214 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0013
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
rs3730358 - rs1130214 - rs3803300 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0035
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Karege, F.,2010 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
G-C-T |
GRIN2B
|
P-value = 0.995395,......
P-value = 0.995395, Z=0.006 in schizophrenia family sample; P-value = 0.008 in schizophrenia case-controls sample
More...
|
Haplotype analyses ......
Haplotype analyses on the schizophrenia case-control sample also showed significant elevation in the frequency of haplotype G-C-T in schizophrenia, and T-C-C in controls. The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Positive |
Martucci, L., 2006 |
|
D22S279 - rs909669 |
|
ADSL
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0805, CLUMP T4 P-value = 0.0501 in BPD and SZ, CLUMP T1 P-value = 0.0447, CLUMP T4 P-value = 0.008 in SZ; Empirical overall P-value = 0.049 in BPD and SZ, Empirical overall P-value = 0.0012 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
D22S279 - rs133068 - rs133069 - rs133070 - rs133073 |
7-C-C-A-T |
MCHR1
|
|
D22S279 - rs133068 - rs133069 - rs133070 - rs133073 |
6/7-C-C-A-T |
MCHR1
|
|
rs133068 - D22S279 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.1818, CLUMP T4 P-value = 0.127 in BPD and SZ, CLUMP T1 P-value = 0.0542, CLUMP T4 P-value = 0.0476 in SZ; Empirical overall P-value = 0.1821 in BPD and SZ, Empirical overall P-value = 0.0054 in SZ
More...
|
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133069 - rs133068 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0716, CLUMP T4 P-value = 0.1107 in BPD and SZ, CLUMP T1 P-value = 0.0469, CLUMP T4 P-value = 0.0353 in SZ; Empirical overall P-value = 0.1791 in BPD and SZ, Empirical overall P-value = 0.1238 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133069 - rs133068 - D22S279 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.2017, CLUMP T4 P-value = 0.2023 in BPD and SZ, CLUMP T1 P-value = 0.187, CLUMP T4 P-value = 0.1727 in SZ; Empirical overall P-value = 0.3066 in BPD and SZ, Empirical overall P-value = 0.0005 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133069 - rs133070 |
A-G |
MCHR1
|
CLUMP P-value = 0.3......
CLUMP P-value = 0.3279 in SZ, P-value = 0.0364 in BPD and SZ; protective haplotype
More...
|
The same specific 2......
The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133070 - rs133069 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0145, CLUMP T4 P-value = 0.0828 in BPD and SZ, CLUMP T1 P-value = 0.3299, CLUMP T4 P-value = 0.3299 in SZ; Empirical overall P-value = 0.4592 in BPD and SZ, Empirical overall P-value = 0.0618 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs1503491 - rs553950 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.024 for Scottish 1, P-value = 0.87 for Scottish 2, P-value = 0.096 for merged Scottish
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs1503491 - rs553950 - rs327329 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.00032 for Scottish 1, P-value = 0.61 for Scottish 2, P-value = 0.028 for merged Scottish
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs133070 - rs133069 - rs133068 - D22S279 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0064, CLUMP T4 P-value = 0.0023 in BPD and SZ, CLUMP T1 P-value = 0.0426, CLUMP T4 P-value = 0.0367 in SZ; Empirical overall P-value = 0.3363 in BPD and SZ, Empirical overall P-value = 0.0053 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs2919390 - rs6988339 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.0012 for Scottish 1, P-value = 0.31 for German
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs133070 - rs133073 |
A-C |
MCHR1
|
CLUMP P-value = 1 i......
CLUMP P-value = 1 in SZ, P-value = 0.0234 in BPD and SZ; risk haplotype
More...
|
The same specific 2......
The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs2919390 - rs6988339 - rs3757930 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.00014 for Scottish 1, P-value = 0.17 for German
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs133070 - rs133073 |
G-C |
MCHR1
|
CLUMP P-value = 0.3......
CLUMP P-value = 0.3286 in SZ, P-value = 0.0183 in BPD and SZ; protective haplotype
More...
|
The same specific 2......
The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs553950 - rs327329 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.0085 for Scottish 1, P-value = 0.68 for Scottish 2, P-value = 0.074 for merged Scottish
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs133073 - rs133070 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.004, CLUMP T4 P-value = 0.0188 in BPD and SZ, CLUMP T1 P-value = 0.5104, CLUMP T4 P-value = 0.5104 in SZ; Empirical overall P-value = 0.0262 in BPD and SZ, Empirical overall P-value = 0.1879 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs6988339 - rs3757930 |
|
NRG1
|
Haplotypic associat......
Haplotypic association:P-value = 0.0014 for Scottish 1, P-value = 0.48 for Scottish 2, P-value = 0.26 for German, P-value = 0.0037 for merged Scottish, P-value = 0.098 for merged all
More...
|
Significant associa......
Significant association was found in SZ.
More...
|
Positive |
Walker, R. M.,2010 |
|
rs133073 - rs133070 - rs133069 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0268, CLUMP T4 P-value = 0.0626 in BPD and SZ, CLUMP T1 P-value = 0.3269, CLUMP T4 P-value = 0.3269 in SZ; Empirical overall P-value = 0.0155 in BPD and SZ, Empirical overall P-value = 0.0148 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133073 - rs133070 - rs133069 - rs133068 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0479, CLUMP T4 P-value = 0.1278 in BPD and SZ, CLUMP T1 P-value = 0.4486, CLUMP T4 P-value = 0.4486 in SZ; Empirical overall P-value = 0.0184 in BPD and SZ, Empirical overall P-value = 0.0135 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133068 - D22S279 - rs909669 |
|
MCHR1
ADSL
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.4823, CLUMP T4 P-value = 0.3996 in BPD and SZ, CLUMP T1 P-value = 0.099, CLUMP T4 P-value = 0.0353 in SZ; Empirical overall P-value = 0.0319 in BPD and SZ, Empirical overall P-value = 0.0015 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs133069 - rs133068 - D22S279 - rs909669 |
|
MCHR1
ADSL
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.2672, CLUMP T4 P-value = 0.2064 in BPD and SZ, CLUMP T1 P-value = 0.1481, CLUMP T4 P-value = 0.0495 in SZ; Empirical overall P-value = 0.0591 in BPD and SZ, Empirical overall P-value = 0.0012 in SZ
More...
|
Similarly, comparin......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs1170099 - rs9566940 |
G-T |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.0002, permutated P-value = 0.002 for SCZ
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Zeng, Z.,2011 |
|
rs133070 - rs133069 - rs133068 - D22S279 - rs909669 |
|
MCHR1
ADSL
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0059, CLUMP T4 P-value = 0.0031 in BPD and SZ, CLUMP T1 P-value = 0.0156, CLUMP T4 P-value = 0.0054 in SZ; Empirical overall P-value = 0.339 in BPD and SZ, Empirical overall P-value = 0.0497 in SZ
More...
|
When comparing cont......
When comparing controls to SZ unequal haplotype distribution was observed for 2-, 3-, 4-, and 5-marker haplotypes spanning all four SNPs in GPR24 in addition to rs909669 in ADSL with a 5- marker haplotype showing a T4 P-value of 0.0054.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs909669 - D22S279 - rs133068 - rs133069 - rs133070 |
C-7-C-C-A |
MCHR1
ADSL
|
CLUMP P-value = 5E-......
CLUMP P-value = 5E-06 in SZ, P-value = 0.0006 in BPD and SZ; risk haplotype
More...
|
The specific 5-mark......
The specific 5-marker haplotype straddling rs909660 to rs133070 as seen inSZ (C7CCA) showed aP-value of 0.0006 in the combined sample, and together with a variant of this haplotype (C6CCA) the haplotypes C-6/7-CCA were over-represented in cases with a frequency of 75% against only 22% in controls.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs909669 - D22S279 - rs133068 - rs133069 - rs133070 |
C-6/7-C-C-A |
MCHR1
ADSL
|
CLUMP P-value = 0.0......
CLUMP P-value = 0.0002 in SZ, P-value = 7E-05 in BPD and SZ; risk haplotype
More...
|
The specific 5-mark......
The specific 5-marker haplotype straddling rs909660 to rs133070 as seen inSZ (C7CCA) showed aP-value of 0.0006 in the combined sample, and together with a variant of this haplotype (C6CCA) the haplotypes C-6/7-CCA were over-represented in cases with a frequency of 75% against only 22% in controls.
More...
|
Positive |
Severinsen, J. E., 2006 (a) |
|
rs9315885 - rs9532988 - rs1012053 |
T-A-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.0005, permutated P-value = 0.005 for SCZ
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Zeng, Z.,2011 |
|
rs12778366 - rs2273773 - rs4746720 - rs10997875 |
T-T-C-T |
SIRT1
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=8.19, OR=0.25, 95%CI=0.181-0.345, individual P-value = 0.00421, corrected P-value = 0.0211 for SZ
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Kishi, T.,2011(a) |
|
rs1954787 - rs4935752 |
|
GRIK4
|
P-value = 0.008 bet......
P-value = 0.008 between SCZ cases and controls; P-value = 0.088 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs1954787 - rs4935752 - rs6589846 |
|
GRIK4
|
P-value = 0.024 bet......
P-value = 0.024 between SCZ cases and controls; P-value = 0.287 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs12778366 - rs2273773 - rs4746720 - rs10997875 |
T-T-T-T |
SIRT1
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=77.1, OR=1, 95%CI=1.00-1.00, individual P-value = 1.63E-17, corrected P-value = 8.15E-17 for SZ
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Kishi, T.,2011(a) |
|
rs2156635 - rs949056 |
|
GRIK4
|
P-value = 0.004 bet......
P-value = 0.004 between SCZ cases and controls; P-value = 0.027 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs2156635 - rs949056 - rs949054 |
|
GRIK4
|
P-value = 0.04 betw......
P-value = 0.04 between SCZ cases and controls; P-value = 0.129 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs2284031 - rs909486 - rs738149 |
C-T-G |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for SZ, P-value(odds ratio)=0.014(0.85)
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Chen, P.,2011 |
|
rs2284031 - rs909486 - rs738149 |
T-C-A |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for SZ, P-value(odds ratio)=0.006(1.37)
More...
|
Significant associa......
Significant association was observed in SZ.
More...
|
Positive |
Chen, P.,2011 |
|
rs2282586 - rs1944522 |
|
GRIK4
|
P-value = 0.708 bet......
P-value = 0.708 between SCZ cases and controls; P-value = 0.048 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs766288 - rs3738401 - rs2812393 - rs821616 |
C-G-G-T |
TSNAX
DISC1
|
P-value=0.0189 for ......
P-value=0.0189 for SCZ, P-value=0.0065 for BPAD&SCZ, P-value=0.0205 for BPAD males & SCZ males
More...
|
C-G-G-T haplotype s......
C-G-G-T haplotype showed relatively lesser frequency in BPAD (P=0.028), SCZ (P=0.0189) and combined cases of BPAD or SCZ (P=0.0065) and combined males of BPAD or SCZ (P=0.0205) compared with controls.
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs2852217 - rs879602 - rs1954787 |
|
GRIK4
|
P-value = 0.03 betw......
P-value = 0.03 between SCZ cases and controls; P-value = 0.039 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs766288 - rs3738401 - rs2812393 - rs821616 |
A-G-G-T |
TSNAX
DISC1
|
P-value=0.0469 for ......
P-value=0.0469 for BPAD&SZ, P-value=0.0209 for BPAD females &SCZ females
More...
|
Haplotype A-G-G-T w......
Haplotype A-G-G-T was also underrepresented in combined cases of BPAD or SCZ (P=0.0469), BPAD females (P=0.0273) and pooled females of BPAD or SCZ (P=0.0209).
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs2852217 - rs879602 - rs1954787 - rs4935752 |
|
GRIK4
|
P-value = 0.006 bet......
P-value = 0.006 between SCZ cases and controls; P-value = 0.041 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs766288 - rs821616 |
C-A |
TSNAX
DISC1
|
P-value=0.082 for S......
P-value=0.082 for SCZ, P-value=0.019 for combined cases, P-value=0.011 for SCZ females, P-value=0.004 for combined females, P-value=0.901 for SCZ males, P-value=0.589 for combined males
More...
|
Allelic combination......
Allelic combination C-A (P=0.004) in the female cases with combined phenotype showed significant association when multiple corrections were performed for all tests within each stratified gender (combined, females, males).
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs766288 - rs821616 |
A-A |
TSNAX
DISC1
|
P-value=0.42 for SC......
P-value=0.42 for SCZ, P-value=0.831 for combined cases, P-value=0.074 for SCZ females, P-value=0.022 for combined females, P-value=0.016 for SCZ males, P-value=0.028 for combined males
More...
|
Few additional comb......
Few additional combinations that were found to be significantly associated after multiple corrections (n=12) were A-T in BPAD females (P=0.012, protective combination); C-A (P=0.014, risk combination), C-A in SCZ females (P=0.011, risk combination), A-T in combined female cases (P=0.012, protective combination) and A-A in combined female cases (P=0.022, protective combination) compared with control females. However nominal significance observed in BPAD (C-A, P=0.024, risk combination), cases with the combined phenotype (C-A, P=0.019, risk combination), SCZ males (A-A, P=0.016, risk combination) and males with the combined phenotype (A-A, P=0.028, risk combination), which did not withstand the multiple corrections.
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs766288 - rs821616 |
A-T |
TSNAX
DISC1
|
P-value=0.577 for S......
P-value=0.577 for SCZ, P-value=0.215 for combined cases, P-value=0.097 for SCZ females, P-value=0.012 for combined females, P-value=0.476 for SCZ males, P-value=0.606 for combined males
More...
|
Few additional comb......
Few additional combinations that were found to be significantly associated after multiple corrections (n=12) were A-T in BPAD females (P=0.012, protective combination); C-A (P=0.014, risk combination), C-A in SCZ females (P=0.011, risk combination), A-T in combined female cases (P=0.012, protective combination) and A-A in combined female cases (P=0.022, protective combination) compared with control females. However nominal significance observed in BPAD (C-A, P=0.024, risk combination), cases with the combined phenotype (C-A, P=0.019, risk combination), SCZ males (A-A, P=0.016, risk combination) and males with the combined phenotype (A-A, P=0.028, risk combination), which did not withstand the multiple corrections.
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs766288 - rs2812393 |
C-C |
TSNAX
DISC1
|
P-value=0.099 for S......
P-value=0.099 for SCZ, P-value=0.016 for combined cases, P-value=0.011 for SCZ females, P-value=0.001 for combined females, P-value=0.993 for SCZ males, P-value=0.703 for combined males
More...
|
Analyses of these t......
Analyses of these two SNPs showed significant associations with allelic combination C-C (P=0.009) in the BPAD phenotype when multiple corrections were performed for all tests within each stratified gender (combined, females, males).
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs766288 - rs2812393 |
A-G |
TSNAX
DISC1
|
P-value=0.62 for SC......
P-value=0.62 for SCZ, P-value=0.551 for combined cases, P-value=0.016 for SCZ females, P-value=0.013 for combined females, P-value=0.174 for SCZ males, P-value=0.212 for combined males
More...
|
Other combinations ......
Other combinations in BPAD females (C-C, P=0.003, risk combination) and SCZ females (C-C, P=0.011, risk combination; A-G, P=0.016, protective combination), combined female cases (A-G, P=0.013, protective combination; C-C, P=0.001, risk combination) were found to be significantly associated after FDR corrections.
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs2812393 - rs821616 |
G-T |
DISC1
|
P-value=0 for SCZ, ......
P-value=0 for SCZ, P-value=0.001 for combined cases, P-value=0.007 for SCZ females, P-value=0.005 for combined females, P-value=0.02 for SCZ males, P-value=0.039 for combined males
More...
|
Allelic combination......
Allelic combinations of G-T in SCZ (P=0), combined cases of BPAD or SCZ (P=0.001), SCZ females (P=0.007) and combined females (P=0.005) were observed to be protective combination of alleles. These combinations survived multiple corrections. In addition allelic combinations of G-T showed nominal significance, but did not withstand FDR corrections.
More...
|
Positive |
Ram Murthy, A., 2012 |
|
rs4586379 - rs2035645 - rs4777974 - rs11637898 - rs11074070 - rs3784735 |
A-A-G-G-A-A |
ST8SIA2
|
P-value = 0.004, X&......
P-value = 0.004, X<sup>2</sup>=8.41, OR (95% CI)=1.82 (1.2-2.74) in Aus SZ
More...
|
We found that the s......
We found that the specific AAGGAA risk haplotype was significantly over-represented in schizophrenia cases compared to controls when a conditional analysis was performed.
More...
|
Positive |
McAuley, E. Z., 2012 |
|
rs4586379 - rs2035645 - rs4777974 - rs11637898 - rs11074070 - rs3784735 |
G-C-A-A-C-C |
ST8SIA2
|
P-value = 0.021, X&......
P-value = 0.021, X<sup>2</sup>=5.30, OR (95% CI)=0.515 (0.29-0.92) in Aus SZ
More...
|
the protective hapl......
the protective haplotype was over-represented in controls on conditional haplotype analysis
More...
|
Positive |
McAuley, E. Z., 2012 |
|
rs4935752 - rs6589846 |
|
GRIK4
|
P-value = 0.005 bet......
P-value = 0.005 between SCZ cases and controls; P-value = 0.103 between all cases and controls
More...
|
These positionally ......
These positionally bi-partite findings were further supported by a sliding window global analysis of haplotypes of lengths two to four, such that distinct clusters of significant P-values were observed in schizophrenia (best global haplotype, SNPs 15 and 16; P = 0.005).
More...
|
Positive |
Pickard, B. S., 2006 |
|
rs4935752 - rs6589846 - rs4430518 |
|
GRIK4
|
P-value = 0.015 bet......
P-value = 0.015 between SCZ cases and controls; P-value = 0.16 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs4935752 - rs6589846 - rs4430518 - rs433110 |
|
GRIK4
|
P-value = 0.016 bet......
P-value = 0.016 between SCZ cases and controls; P-value = 0.128 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs6589846 - rs4430518 |
|
GRIK4
|
P-value = 0.007 bet......
P-value = 0.007 between SCZ cases and controls; P-value = 0.115 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs7111184 - rs2156635 - rs949056 |
|
GRIK4
|
P-value = 0.045 bet......
P-value = 0.045 between SCZ cases and controls; P-value = 0.173 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs879602 - rs1954787 - rs4935752 - rs6589846 |
|
GRIK4
|
P-value = 0.028 bet......
P-value = 0.028 between SCZ cases and controls; P-value = 0.176 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
rs948028 - rs2852217 - rs879602 - rs1954787 |
|
GRIK4
|
P-value = 0.043 bet......
P-value = 0.043 between SCZ cases and controls; P-value = 0.005 between all cases and controls
More...
|
|
Positive |
Pickard, B. S., 2006 |
|
D22S922 - D22S1169 - rs4468 |
2-3-C |
BRD1
|
|
rs138855 - rs138880 |
G-C |
BRD1
|
P-value = 1E-06 in ......
P-value = 1E-06 in BD, P-value = 2.8E-07 in BD and SZ
More...
|
Removing the rare m......
Removing the rare middle SNP rs2239848 from the analysis resulted in a reduced 2-marker 'risk' haplotype (G-C) showing a frequency of ~10% in cases versus ~1% in controls.
More...
|
Positive |
Severinsen, J. E., 2006 (b) |
|
rs138855 - rs138880 - rs138881 |
G-C-A |
BRD1
|
|
rs138855 - rs138880 - rs138881 |
G-C-G |
BRD1
|
|
rs138855 - rs2239848 - rs138880 |
G-G-C |
BRD1
|
P-value = 4E-06 in ......
P-value = 4E-06 in BD, P-value = 1E-06 in BD and SZ
More...
|
A 3-marker core hap......
A 3-marker core haplotype spanning BRD1 SNPs rs138855, rs2239848 and rs138880 had a frequency of around 9% in cases against only 1% in controls, producing a haplotype specific P-value of order 1E-06.
More...
|
Positive |
Severinsen, J. E., 2006 (b) |
|
rs138855 - rs2239848 - rs138880 - rs138881 |
G-G-C-A |
BRD1
|
|
rs138880 - rs2239848 |
|
BRD1
|
|
rs138880 - rs2239848 - rs138855 |
|
BRD1
|
P-value = 0.00001 i......
P-value = 0.00001 in SZ, P-value = 0.00005 in BD and SZ
More...
|
Highly significant ......
Highly significant overall P-values (as low as 0.00001) were observed in especially the 3- and 4-marker analysis involving the BRD1 SNPs rs138855, rs2239848, rs138880 and rs138881.
More...
|
Positive |
Severinsen, J. E., 2006 (b) |
|
rs138880 - rs2239848 - rs138855 - rs4468 |
|
BRD1
|
|
rs138881 - rs138880 - rs2239848 - rs138855 |
|
BRD1
|
P-value = 0.0002 in......
P-value = 0.0002 in SZ, P-value = 0.0003 in BD and SZ
More...
|
Highly significant ......
Highly significant overall P-values (as low as 0.00001) were observed in especially the 3- and 4-marker analysis involving the BRD1 SNPs rs138855, rs2239848, rs138880 and rs138881.
More...
|
Positive |
Severinsen, J. E., 2006 (b) |
|
rs2239848 - rs138855 - rs4468 |
|
BRD1
|
|
rs2239848 - rs138855 - rs4468 - D22S1169 |
|
BRD1
|
|
rs4468 - D22S1169 |
|
BRD1
|
|
rs4468 - D22S1169 - D22S922 - rs132234 |
|
BRD1
FAM19A5
|
|
D22S1169 - D22S922 - rs132234 |
|
FAM19A5
|
|
D22S1169 - D22S922 |
|
|
|
rs10095694 - rs2919390 |
|
NRG1
|
|
rs10095694 - rs2919390 - rs6988339 |
|
NRG1
|
|
rs10095694 - rs2919390 - rs6988339 - rs3757930 |
|
NRG1
|
|
rs10113797 - rs10954811 - rs1503491 - rs553950 |
|
NRG1
|
|
rs10954811 - rs1503491 - rs553950 |
|
NRG1
|
|
rs10954811 - rs1503491 - rs553950 - rs327329 |
|
NRG1
|
|
rs1503491 - rs553950 |
|
NRG1
|
|
rs1503491 - rs553950 - rs327329 |
T-T-T |
NRG1
|
P-value = 0.0003 fo......
P-value = 0.0003 for SZ, P-value = 0.0017 for SZ and BP combined
More...
|
3-SNP haplotype is ......
3-SNP haplotype is nominally significant with SCZ alone, but it does not withstand permutation analysis
More...
|
Positive |
Thomson, P. A., 2007 |
|
rs1503491 - rs553950 - rs327329 - rs7007662 |
|
NRG1
|
|
rs2439286 - rs10095694 |
|
NRG1
|
|
rs2439286 - rs10095694 - rs2919390 |
|
NRG1
|
|
rs2439286 - rs10095694 - rs2919390 - rs6988339 |
|
NRG1
|
|
(RGS4_SNP1) - (RGS4_SNP4) - (RGS4_SNP7) - (RGS4_SNP18) |
|
RGS4
|
Estimated haplotype......
Estimated haplotype frequencies among cases and unrelated controls:P>0.05
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Chowdari, K. V.,2002 |
|
(HTR4_SVRSNP1) - (HTR4_SVRSNP4) |
C-A |
HTR4
|
Haplotype analysis:......
Haplotype analysis:Transmission disequilibrium test:Schizophrenia(RIKEN families):T/NT=16/20, chi square=0.4, P-value = 0.5
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Ohtsuki, T.,2002 |
|
(HTR4_SVRSNP1) - (HTR4_SVRSNP4) |
T-G |
HTR4
|
Haplotype analysis:......
Haplotype analysis:Transmission disequilibrium test:Schizophrenia(RIKEN families):T/NT=25/21, chi square=0.35, P-value = 0.56
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Ohtsuki, T.,2002 |
|
(GPR50_502-505) - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for SCZ, P-value = 0.18(all), 0.3(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative |
Thomson, P. A.,2005(b) |
|
rs2072621 - (GPR50_502-505) |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for SCZ, P-value = 0.16(all), 0.3(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative |
Thomson, P. A.,2005(b) |
|
rs2072621 - (GPR50_502-505) - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for SCZ, P-value = 0.078(all), 0.068(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative |
Thomson, P. A.,2005(b) |
|
rs2072621 - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for SCZ, P-value = 0.63(all), 0.76(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative |
Thomson, P. A.,2005(b) |
|
rs2271309 - rs12601930 - rs907094 - rs3764352 |
|
PPP1R1B
|
Global P-value = 0.......
Global P-value = 0.697
More...
|
Haplotypic analyses......
Haplotypic analyses of four SNPs in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia.
More...
|
Negative |
Yoshimi, A., 2008 |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
|
PAWR
|
|
rs960914 - rs2241802 - rs2323019 - rs352203 |
|
FZD3
|
Haplotypic associat......
Haplotypic association:global P-values>0.2
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Hashimoto, R.,2005(b) |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAGTA |
PAWR
|
|
RGS4_SNP1 - RGS4_SNP4 - RGS4_SNP17 - RGS4_SNP18 |
G-G-G-G |
RGS4
|
Haplotypic associat......
Haplotypic association:Family-based analysis:TDT:X<sup>2</sup>=2.67, P-value = 0.102 in SZ
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Cordeiro, Q.,2005 |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAACG |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
ATGCA |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAGCG |
PAWR
|
|
rs1954175 - rs1538977 - rs2492367 |
|
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.19(all), 0.037(male), 0.81(female);
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Thomson, P. A.,2005(a) |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
AAGCA |
PAWR
|
|
rs2492367 - rs2812393 - rs1322784 |
C-G-T |
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value > 0.05(all)
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Thomson, P. A.,2005(a) |
|
rs11939815 - rs11931061 - rs11133385 - rs3736544 - rs1801260 - rs3749474 |
|
CLOCK
|
likelihood ratio te......
likelihood ratio test:haplotype(G-A-A-G-T-T):1.total samples:Global P-value = 0.340 in SCZ 2. male samples:Global P-value = 0.464 in SCZ 3. female samples:Global P-value = 0.0362, Corrected P-value = 0.0724 in SCZ
More...
|
Only one associatio......
Only one association, with schizophrenia in females, was detected in the haplotype analysis (P = 0.0362). However, this significance did not remain after Bonferroni correction (P = 0.0724).
More...
|
Negative |
Kishi, T.,2009(a) |
|
rs2812393 - rs1322784 - rs2759346 - rs6675281 |
|
TSNAX
DISC1
|
Global association ......
Global association test:for SCZ, P-value = 0.15(all), 0.84(male), 0.04(female);
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Thomson, P. A.,2005(a) |
|
rs2076127 - ss16339182 |
A-T |
MLC1
|
Haplotypic associat......
Haplotypic association:for SCZ, global P-value > 0.05, individual P-value > 0.05, odds ratio=0.95, 95%CI=0.63-1.44
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Verma, R.,2005(b) |
|
rs2076127 - ss16339182 |
G-C |
MLC1
|
Haplotypic associat......
Haplotypic association:for SCZ, global P-value > 0.05, individual P-value > 0.05, odds ratio=1.2, 95%CI=0.79-1.82
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Verma, R.,2005(b) |
|
rs2076127 - ss16339182 |
G-T |
MLC1
|
Haplotypic associat......
Haplotypic association:for SCZ, global P-value > 0.05, individual P-value > 0.05, odds ratio=0.98, 95%CI=0.70-1.37
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Verma, R.,2005(b) |
|
rs1050565 - rs2020934 |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.651
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
rs1050565 - rs2020934 - SLC6A4_5HTTVNTR |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.376
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
rs1050565 - rs2020934 - SLC6A4_5HTTVNTR - rs3813034 |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.715
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
rs2020934 - SLC6A4_5HTTVNTR |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.701
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
rs2020934 - SLC6A4_5HTTVNTR - rs3813034 |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.545
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
SLC6A4_5HTTVNTR - rs3813034 |
|
SLC6A4
|
global P-value = 0.......
global P-value = 0.151
More...
|
We found no associa......
We found no association with SCZ in the haplotype-wise association analysis.
More...
|
Negative |
Ikeda, M., 2006 |
|
PRODH1945 - PRODH1482 |
|
PRODH
|
Haplotypic associat......
Haplotypic association:Global P-value = 0.339(based on 100, 000 replications) for SZ.
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Abou Jamra, R.,2005(a) |
|
rs1130214 - rs3803300 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.605
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Karege, F.,2010 |
|
PRODH2026 - PRODH1945 |
|
PRODH
|
Haplotypic associat......
Haplotypic association:Global P-value = 0.641(based on 100, 000 replications) for SZ.
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Abou Jamra, R.,2005(a) |
|
PRODH2026 - PRODH1945 - PRODH1482 |
|
PRODH
|
Haplotypic associat......
Haplotypic association:Global P-value = 0.458(based on 100, 000 replications) for SZ.
More...
|
No significant ass......
No significant association was found .
More...
|
Negative |
Abou Jamra, R.,2005(a) |
|
32416574(G/A) - IVS4+1008ins(T)/del(T) |
|
SLC12A6
|
Association test fo......
Association test for heterogeneity, for SZ, empirical P-value = 0.2176
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Meyer, J.,2005 |
|
32418760(G/A) - 32416574(G/A) |
|
SLC12A6
|
Association test fo......
Association test for heterogeneity, for SZ, empirical P-value = 0.2467
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Meyer, J.,2005 |
|
32418760(G/A) - 32416574(G/A) - IVS4+1008ins(T)/del(T) |
|
SLC12A6
|
Association test fo......
Association test for heterogeneity, for SZ, empirical P-value = 0.1382
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Meyer, J.,2005 |
|
32418760(G/A) - IVS4+1008ins(T)/del(T) |
|
SLC12A6
|
Association test fo......
Association test for heterogeneity, for SZ, empirical P-value = 0.0751
More...
|
No significant asso......
No significant associations were found in SZ.
More...
|
Negative |
Meyer, J.,2005 |
|
GSK-3 beta_-1727A/T - GSK-3 beta_-50C/T |
A-C, A-T, T-C, T-T |
GSK3B
|
P-value = 0.81 for ......
P-value = 0.81 for BD, P-value = 0.54 for BD and SZ
More...
|
There was no differ......
There was no difference in the haplotype frequency combination between the patient and control groups.
More...
|
Negative |
Lee, K. Y., 2006 (b) |
|
rs2498804 - rs2494732 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.0861
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Karege, F.,2010 |
|
rs2498804 - rs2494732 - rs1130233 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.395
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Karege, F.,2010 |
|
rs2498804 - rs2494732 - rs1130233 - rs3730358 |
|
AKT1
|
multi-locus associa......
multi-locus association analyses:global P-value = 0.197
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Karege, F.,2010 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
T-A-C |
GRIN2B
|
P-value = 0.242452,......
P-value = 0.242452, Z=1.169 in schizophrenia family sample; P-value = 0.116 in schizophrenia case-controls sample
More...
|
The overall differe......
The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Negative |
Martucci, L., 2006 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
G-C-C |
GRIN2B
|
P-value = 0.650714,......
P-value = 0.650714, Z=-0.453 in schizophrenia family sample; P-value = 0.104 in schizophrenia case-controls sample
More...
|
The overall differe......
The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Negative |
Martucci, L., 2006 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
G-A-C |
GRIN2B
|
P-value = 0.324213,......
P-value = 0.324213, Z=0.986 in schizophrenia family sample; P-value = 0.013 in schizophrenia case-controls sample
More...
|
The overall differe......
The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Negative |
Martucci, L., 2006 |
|
GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C |
T-C-T |
GRIN2B
|
P-value = 0.102451,......
P-value = 0.102451, Z=-1.633 in schizophrenia family sample; P-value = 0.271 in schizophrenia case-controls sample
More...
|
The overall differe......
The overall difference in haplotype transmission between cases and controls is statistically significant (p =0.005).
More...
|
Negative |
Martucci, L., 2006 |
|
D22S279 - rs133068 - rs133069 - rs133070 - rs133073 |
6-C-C-A-T |
MCHR1
|
|
rs133069 - rs133070 - rs133073 |
A-G-C |
MCHR1
|
CLUMP P-value = 0.3......
CLUMP P-value = 0.3279 in SZ, P-value = 0.0526 in BPD and SZ; protective haplotype
More...
|
The same specific 2......
The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample.
More...
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs133070 - rs133069 - rs133068 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0525, CLUMP T4 P-value = 0.1831 in BPD and SZ, CLUMP T1 P-value = 0.4456, CLUMP T4 P-value = 0.4456 in SZ; Empirical overall P-value = 0.5945 in BPD and SZ, Empirical overall P-value = 0.0691 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs133073 - rs133070 - rs133069 - rs133068 - D22S279 |
|
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.0063, CLUMP T4 P-value = 0.0023 in BPD and SZ, CLUMP T1 P-value = 0.0432, CLUMP T4 P-value = 0.0375 in SZ; Empirical overall P-value = 0.1747 in BPD and SZ, Empirical overall P-value = 0.0189 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs6295 - rs878567 |
C-C |
HTR1A
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:OR=1.20, 95%CI=0.971-1.47, individual P-value = 0.0921; global P-value = 0.0935
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Kishi, T.,2011(b) |
|
rs6295 - rs878567 |
G-C |
HTR1A
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:OR=1.20, 95%CI=0.971-1.47, individual P-value = 0.0921; global P-value = 0.0935
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Kishi, T.,2011(b) |
|
rs1170099 - rs9566940 |
A-C |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.364, permutated P-value = 0.993 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs1170099 - rs9566940 |
A-T |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.179, permutated P-value = 0.859 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
A-A-C-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 1, permutated P-value = 1 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
A-A-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.623, permutated P-value = 1 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs909669 - D22S279 - rs133068 - rs133069 - rs133070 |
C-6-C-C-A |
MCHR1
ADSL
|
CLUMP P-value = 0.5......
CLUMP P-value = 0.5569 in SZ, P-value = 0.3176 in BPD and SZ; risk haplotype
More...
|
The specific 5-mark......
The specific 5-marker haplotype straddling rs909660 to rs133070 as seen inSZ (C7CCA) showed aP-value of 0.0006 in the combined sample, and together with a variant of this haplotype (C6CCA) the haplotypes C-6/7-CCA were over-represented in cases with a frequency of 75% against only 22% in controls.
More...
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-A-T-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.243, permutated P-value = 0.945 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-A-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.219, permutated P-value = 0.924 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs1573745 - rs710193 |
|
ST13
|
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-G-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.297, permutated P-value = 0.976 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs1573745 - rs710193 - rs133073 |
|
ST13
MCHR1
|
|
rs9315885 - rs9532988 - rs1012053 |
C-A-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.018, permutated P-value = 0.147 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs1573745 - rs710193 - rs133073 - rs133070 |
|
ST13
MCHR1
|
|
rs9315885 - rs9532988 - rs1012053 |
C-A-C |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.116, permutated P-value = 0.719 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs1573745 - rs710193 - rs133073 - rs133070 - rs133069 |
|
ST13
MCHR1
|
|
rs710193 - rs133073 |
|
ST13
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.4522, CLUMP T4 P-value = 0.4361 in BPD and SZ, CLUMP T1 P-value = 0.3844, CLUMP T4 P-value = 0.3368 in SZ; Empirical overall P-value = 0.1247 in BPD and SZ, Empirical overall P-value = 0.3269 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs9315885 - rs9532988 - rs1012053 |
T-G-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value = 0.446, permutated P-value = 0.998 for SCZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Zeng, Z.,2011 |
|
rs710193 - rs133073 - rs133070 |
|
ST13
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.1158, CLUMP T4 P-value = 0.1697 in BPD and SZ, CLUMP T1 P-value = 0.3917, CLUMP T4 P-value = 0.5842 in SZ; Empirical overall P-value = 0.0715 in BPD and SZ, Empirical overall P-value = 0.224 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs12778366 - rs2273773 - rs4746720 - rs10997875 |
C-T-T-T |
SIRT1
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=2.02, OR=0.307, 95%CI=0.217-0.434, individual P-value = 0.155 for SZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Kishi, T.,2011(a) |
|
rs710193 - rs133073 - rs133070 - rs133069 |
|
ST13
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.1755, CLUMP T4 P-value = 0.2417 in BPD and SZ, CLUMP T1 P-value = 0.3957, CLUMP T4 P-value = 0.5862 in SZ; Empirical overall P-value = 0.079 in BPD and SZ, Empirical overall P-value = 0.1069 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs12778366 - rs2273773 - rs4746720 - rs10997875 |
T-C-T-T |
SIRT1
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=0.269, OR=0.271, 95%CI=0.196-0.375, individual P-value = 0.604 for SZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Kishi, T.,2011(a) |
|
rs710193 - rs133073 - rs133070 - rs133069 - rs133068 |
|
ST13
MCHR1
|
CLUMP T1 P-value = ......
CLUMP T1 P-value = 0.1722, CLUMP T4 P-value = 0.239 in BPD and SZ, CLUMP T1 P-value = 0.3932, CLUMP T4 P-value = 0.5852 in SZ; Empirical overall P-value = 0.1895 in BPD and SZ, Empirical overall P-value = 0.146 in SZ
More...
|
|
Negative |
Severinsen, J. E., 2006 (a) |
|
rs12778366 - rs2273773 - rs4746720 - rs10997875 |
T-T-T-C |
SIRT1
|
Haplotype analysis:......
Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=0.525, OR=0.264, 95%CI=0.189-0.371, individual P-value = 0.469 for SZ
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Kishi, T.,2011(a) |
|
rs1954787 - rs4935752 - rs6589846 - rs4430518 |
|
GRIK4
|
P-value = 0.068 bet......
P-value = 0.068 between SCZ cases and controls; P-value = 0.32 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs11759115 - rs7769372 |
C-C |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.1223, individual P-value = 0.046
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs2000869 - rs7479743 |
|
GRIK4
|
P-value = 0.538 bet......
P-value = 0.538 between SCZ cases and controls; P-value = 0.448 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs11759115 - rs7769372 |
T-C |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.1223, individual P-value = 0.3551
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs2000869 - rs7479743 - rs6589832 |
|
GRIK4
|
P-value = 0.466 bet......
P-value = 0.466 between SCZ cases and controls; P-value = 0.391 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs11759115 - rs7769372 |
T-T |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.1223, individual P-value = 0.9978
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs2000869 - rs7479743 - rs6589832 - rs7925270 |
|
GRIK4
|
P-value = 0.365 bet......
P-value = 0.365 between SCZ cases and controls; P-value = 0.483 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs1883901 - rs10807187 - rs9462343 |
A-G-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.404, individual P-value = 0.0732
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
G-G-A |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.404, individual P-value = 1
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
G-G-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.404, individual P-value = 0.4639
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs2156635 - rs949056 - rs949054 - rs602104 |
|
GRIK4
|
P-value = 0.091 bet......
P-value = 0.091 between SCZ cases and controls; P-value = 0.117 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs1883901 - rs10807187 - rs9462343 |
G-T-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for SZ, global P-value = 0.404, individual P-value = 0.9998
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Li, J.,2011(a) |
|
rs2187495 - rs3132780 |
|
GRIK4
|
P-value = 0.819 bet......
P-value = 0.819 between SCZ cases and controls; P-value = 0.495 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2284031 - rs909486 - rs738149 |
C-T-A |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for SZ, P-value(odds ratio)=0.998(1)
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Chen, P.,2011 |
|
rs2187495 - rs3132780 - rs948028 |
|
GRIK4
|
P-value = 0.713 bet......
P-value = 0.713 between SCZ cases and controls; P-value = 0.508 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2187495 - rs3132780 - rs948028 - rs2852217 |
|
GRIK4
|
P-value = 0.827 bet......
P-value = 0.827 between SCZ cases and controls; P-value = 0.774 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2276319 - rs513548 |
|
GRIK4
|
P-value = 0.643 bet......
P-value = 0.643 between SCZ cases and controls; P-value = 0.472 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2284031 - rs909486 - rs738149 |
T-C-G |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for SZ, P-value(odds ratio)=0.263(1.1)
More...
|
No significant asso......
No significant association was observed in SZ.
More...
|
Negative |
Chen, P.,2011 |
|
rs2276319 - rs513548 - rs2282586 |
|
GRIK4
|
P-value = 0.496 bet......
P-value = 0.496 between SCZ cases and controls; P-value = 0.186 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7090018 - rs11199993 |
T-G |
FGFR2
|
P-value = 0.835, Pe......
P-value = 0.835, Permutated P-value = 1.000
More...
|
No significant asso......
No significant association was found
More...
|
Negative |
Wang, T.,2012 |
|
rs2276319 - rs513548 - rs2282586 - rs1944522 |
|
GRIK4
|
P-value = 0.781 bet......
P-value = 0.781 between SCZ cases and controls; P-value = 0.113 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7090018 - rs11199993 |
T-C |
FGFR2
|
P-value = 0.112, Pe......
P-value = 0.112, Permutated P-value = 0.698
More...
|
No significant asso......
No significant association was found
More...
|
Negative |
Wang, T.,2012 |
|
rs7090018 - rs11199993 |
G-G |
FGFR2
|
P-value = 0.103, Pe......
P-value = 0.103, Permutated P-value = 0.664
More...
|
No significant asso......
No significant association was found
More...
|
Negative |
Wang, T.,2012 |
|
rs2852217 - rs879602 |
|
GRIK4
|
P-value = 0.825 bet......
P-value = 0.825 between SCZ cases and controls; P-value = 0.232 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs3132780 - rs948028 |
|
GRIK4
|
P-value = 0.619 bet......
P-value = 0.619 between SCZ cases and controls; P-value = 0.779 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs3132780 - rs948028 - rs2852217 |
|
GRIK4
|
P-value = 0.696 bet......
P-value = 0.696 between SCZ cases and controls; P-value = 0.543 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs766288 - rs821616 |
C-T |
TSNAX
DISC1
|
P-value=0.093 for S......
P-value=0.093 for SCZ, P-value=0.115 for combined cases, P-value=0.307 for SCZ females, P-value=0.489 for combined females, P-value=0.177 for SCZ males, P-value=0.138 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs3132780 - rs948028 - rs2852217 - rs879602 |
|
GRIK4
|
P-value = 0.905 bet......
P-value = 0.905 between SCZ cases and controls; P-value = 0.171 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs3133226 - rs2187495 |
|
GRIK4
|
P-value = 0.98 betw......
P-value = 0.98 between SCZ cases and controls; P-value = 0.492 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs3133226 - rs2187495 - rs3132780 |
|
GRIK4
|
P-value = 0.84 betw......
P-value = 0.84 between SCZ cases and controls; P-value = 0.564 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs3133226 - rs2187495 - rs3132780 - rs948028 |
|
GRIK4
|
P-value = 0.767 bet......
P-value = 0.767 between SCZ cases and controls; P-value = 0.597 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs766288 - rs2812393 |
C-G |
TSNAX
DISC1
|
P-value=0.46 for SC......
P-value=0.46 for SCZ, P-value=0.703 for combined cases, P-value=0.626 for SCZ females, P-value=0.969 for combined females, P-value=0.639 for SCZ males, P-value=0.672 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs3133855 - rs3133226 |
|
GRIK4
|
P-value = 0.985 bet......
P-value = 0.985 between SCZ cases and controls; P-value = 0.971 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs766288 - rs2812393 |
A-C |
TSNAX
DISC1
|
P-value=0.529 for S......
P-value=0.529 for SCZ, P-value=0.632 for combined cases, P-value=0.626 for SCZ females, P-value=0.216 for combined females, P-value=0.175 for SCZ males, P-value=0.099 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs3133855 - rs3133226 - rs2187495 |
|
GRIK4
|
P-value = 0.999 bet......
P-value = 0.999 between SCZ cases and controls; P-value = 0.885 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2812393 - rs821616 |
C-A |
DISC1
|
P-value=0.236 for S......
P-value=0.236 for SCZ, P-value=0.125 for combined cases, P-value=0.078 for SCZ females, P-value=0.077 for combined females, P-value=0.931 for SCZ males, P-value=0.673 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs3133855 - rs3133226 - rs2187495 - rs3132780 |
|
GRIK4
|
P-value = 0.965 bet......
P-value = 0.965 between SCZ cases and controls; P-value = 0.824 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2812393 - rs821616 |
G-A |
DISC1
|
P-value=0.976 for S......
P-value=0.976 for SCZ, P-value=0.806 for combined cases, P-value=0.958 for SCZ females, P-value=0.834 for combined females, P-value=0.941 for SCZ males, P-value=0.898 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs4245040 - rs7928347 |
|
GRIK4
|
P-value = 0.364 bet......
P-value = 0.364 between SCZ cases and controls; P-value = 0.089 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs4245040 - rs7928347 - rs2000869 |
|
GRIK4
|
P-value = 0.704 bet......
P-value = 0.704 between SCZ cases and controls; P-value = 0.288 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs2812393 - rs821616 |
C-T |
DISC1
|
P-value=0.381 for S......
P-value=0.381 for SCZ, P-value=0.531 for combined cases, P-value=0.659 for SCZ females, P-value=0.642 for combined females, P-value=0.119 for SCZ males, P-value=0.206 for combined males
More...
|
|
Negative |
Ram Murthy, A., 2012 |
|
rs4245040 - rs7928347 - rs2000869 - rs7479743 |
|
GRIK4
|
P-value = 0.484 bet......
P-value = 0.484 between SCZ cases and controls; P-value = 0.221 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs433110 - rs7111184 |
|
GRIK4
|
P-value = 0.149 bet......
P-value = 0.149 between SCZ cases and controls; P-value = 0.606 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs4586379 - rs8025225 - rs11074066 - rs11074067 - rs2035645 |
T-T-A-G-T |
ST8SIA2
|
P-value = 0.129, X&......
P-value = 0.129, X<sup>2</sup>=2.30, OR (95% CI)=1.09 (0.97-1.23) in NIMH SZ
More...
|
This haplotype also......
This haplotype also showed the same direction of effect in the NIMH cases with schizophrenia compared to controls, although it did not reach statistical significance.
More...
|
Negative |
McAuley, E. Z., 2012 |
|
rs433110 - rs7111184 - rs2156635 |
|
GRIK4
|
P-value = 0.419 bet......
P-value = 0.419 between SCZ cases and controls; P-value = 0.57 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs433110 - rs7111184 - rs2156635 - rs949056 |
|
GRIK4
|
P-value = 0.305 bet......
P-value = 0.305 between SCZ cases and controls; P-value = 0.707 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs4586379 - rs8025225 - rs11074066 - rs11074067 - rs2035645 |
C-C-C-C-G |
ST8SIA2
|
P-value = 0.408, X&......
P-value = 0.408, X<sup>2</sup>=0.68, OR (95% CI)=0.938 (0.81-1.09) in NIMH SZ
More...
|
No significant asso......
No significant association was reported in this study.
More...
|
Negative |
McAuley, E. Z., 2012 |
|
rs4430518 - rs433110 |
|
GRIK4
|
P-value = 0.14 betw......
P-value = 0.14 between SCZ cases and controls; P-value = 0.769 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs4430518 - rs433110 - rs7111184 |
|
GRIK4
|
P-value = 0.135 bet......
P-value = 0.135 between SCZ cases and controls; P-value = 0.855 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs4430518 - rs433110 - rs7111184 - rs2156635 |
|
GRIK4
|
P-value = 0.367 bet......
P-value = 0.367 between SCZ cases and controls; P-value = 0.758 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7171233 - rs7165988 - rs2172835 |
T-C-C |
C15orf53
|
CHI SQUARE = 1.077,......
CHI SQUARE = 1.077,P-value = 0.2993
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative |
Kranz, T. M.,2012 |
|
rs7171233 - rs7165988 - rs2172835 |
A-G-T |
C15orf53
|
CHI SQUARE = 0.206,......
CHI SQUARE = 0.206,P-value = 0.6502
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative |
Kranz, T. M.,2012 |
|
rs7090018 - rs11199993 |
T-G |
FGFR2
|
P-value=0.835, Perm......
P-value=0.835, Permutated P-value=1
More...
|
No significant asso......
No significant association was found.
More...
|
Negative |
Wang, T.,2012 |
|
rs513548 - rs2282586 |
|
GRIK4
|
P-value = 0.288 bet......
P-value = 0.288 between SCZ cases and controls; P-value = 0.093 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7090018 - rs11199993 |
T-C |
FGFR2
|
P-value=0.112, Perm......
P-value=0.112, Permutated P-value=0.698
More...
|
No significant asso......
No significant association was found.
More...
|
Negative |
Wang, T.,2012 |
|
rs513548 - rs2282586 - rs1944522 |
|
GRIK4
|
P-value = 0.41 betw......
P-value = 0.41 between SCZ cases and controls; P-value = 0.054 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7090018 - rs11199993 |
G-G |
FGFR2
|
P-value=0.103, Perm......
P-value=0.103, Permutated P-value=0.664
More...
|
No significant asso......
No significant association was found.
More...
|
Negative |
Wang, T.,2012 |
|
rs602104 - rs2276319 |
|
GRIK4
|
P-value = 0.908 bet......
P-value = 0.908 between SCZ cases and controls; P-value = 0.274 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs602104 - rs2276319 - rs513548 |
|
GRIK4
|
P-value = 0.781 bet......
P-value = 0.781 between SCZ cases and controls; P-value = 0.314 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs602104 - rs2276319 - rs513548 - rs2282586 |
|
GRIK4
|
P-value = 0.695 bet......
P-value = 0.695 between SCZ cases and controls; P-value = 0.34 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs6589832 - rs7925270 |
|
GRIK4
|
P-value = 0.474 bet......
P-value = 0.474 between SCZ cases and controls; P-value = 0.913 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs6589832 - rs7925270 - rs3133855 |
|
GRIK4
|
P-value = 0.837 bet......
P-value = 0.837 between SCZ cases and controls; P-value = 0.8 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs6589832 - rs7925270 - rs3133855 - rs3133226 |
|
GRIK4
|
P-value = 0.833 bet......
P-value = 0.833 between SCZ cases and controls; P-value = 0.831 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs6589846 - rs4430518 - rs433110 |
|
GRIK4
|
P-value = 0.059 bet......
P-value = 0.059 between SCZ cases and controls; P-value = 0.34 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs6589846 - rs4430518 - rs433110 - rs7111184 |
|
GRIK4
|
P-value = 0.055 bet......
P-value = 0.055 between SCZ cases and controls; P-value = 0.335 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7111184 - rs2156635 |
|
GRIK4
|
P-value = 0.363 bet......
P-value = 0.363 between SCZ cases and controls; P-value = 0.277 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7111184 - rs2156635 - rs949056 - rs949054 |
|
GRIK4
|
P-value = 0.118 bet......
P-value = 0.118 between SCZ cases and controls; P-value = 0.271 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7479743 - rs6589832 |
|
GRIK4
|
P-value = 0.87 betw......
P-value = 0.87 between SCZ cases and controls; P-value = 0.779 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7479743 - rs6589832 - rs7925270 |
|
GRIK4
|
P-value = 0.597 bet......
P-value = 0.597 between SCZ cases and controls; P-value = 0.718 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7479743 - rs6589832 - rs7925270 - rs3133855 |
|
GRIK4
|
P-value = 0.757 bet......
P-value = 0.757 between SCZ cases and controls; P-value = 0.712 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7925270 - rs3133855 |
|
GRIK4
|
P-value = 0.952 bet......
P-value = 0.952 between SCZ cases and controls; P-value = 0.95 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7925270 - rs3133855 - rs3133226 |
|
GRIK4
|
P-value = 0.886 bet......
P-value = 0.886 between SCZ cases and controls; P-value = 0.876 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7925270 - rs3133855 - rs3133226 - rs2187495 |
|
GRIK4
|
P-value = 0.984 bet......
P-value = 0.984 between SCZ cases and controls; P-value = 0.86 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7928347 - rs2000869 |
|
GRIK4
|
P-value = 0.735 bet......
P-value = 0.735 between SCZ cases and controls; P-value = 0.583 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7928347 - rs2000869 - rs7479743 |
|
GRIK4
|
P-value = 0.612 bet......
P-value = 0.612 between SCZ cases and controls; P-value = 0.43 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7928347 - rs2000869 - rs7479743 - rs6589832 |
|
GRIK4
|
P-value = 0.187 bet......
P-value = 0.187 between SCZ cases and controls; P-value = 0.306 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs62510682 - rs6994992 |
G-T |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.026, P-value=1, P-value(uncorrected)=0.8711
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs879602 - rs1954787 |
|
GRIK4
|
P-value = 0.702 bet......
P-value = 0.702 between SCZ cases and controls; P-value = 0.949 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs62510682 - rs6994992 |
G-C |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.056, P-value=0.996, P-value(uncorrected)=0.8134
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs879602 - rs1954787 - rs4935752 |
|
GRIK4
|
P-value = 0.067 bet......
P-value = 0.067 between SCZ cases and controls; P-value = 0.449 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs62510682 - rs6994992 |
T-C |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.015, P-value=1, P-value(uncorrected)=0.9031
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs7005606 - rs6468119 - rs3802158 - rs7834206 |
T-T-C-C |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.166, P-value=0.9972, P-value(uncorrected)=0.684
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs948028 - rs2852217 |
|
GRIK4
|
P-value = 0.598 bet......
P-value = 0.598 between SCZ cases and controls; P-value = 0.383 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7005606 - rs6468119 - rs3802158 - rs7834206 |
G-C-T-A |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.649, P-value=0.9316, P-value(uncorrected)=0.4205
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs948028 - rs2852217 - rs879602 |
|
GRIK4
|
P-value = 0.938 bet......
P-value = 0.938 between SCZ cases and controls; P-value = 0.158 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs7005606 - rs6468119 - rs3802158 - rs7834206 |
T-C-C-C |
NRG1
|
Schizophrenia patie......
Schizophrenia patients: χ2=0.095, P-value=0.9990, P-value(uncorrected)=0.7574
More...
|
No significant asso......
No significant association between this block and SZ was observed.
More...
|
Negative |
Gutierrez-Fernandez, A., 2014 |
|
rs949054 - rs602104 |
|
GRIK4
|
P-value = 0.769 bet......
P-value = 0.769 between SCZ cases and controls; P-value = 0.093 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs949054 - rs602104 - rs2276319 |
|
GRIK4
|
P-value = 0.99 betw......
P-value = 0.99 between SCZ cases and controls; P-value = 0.589 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs949054 - rs602104 - rs2276319 - rs513548 |
|
GRIK4
|
P-value = 0.945 bet......
P-value = 0.945 between SCZ cases and controls; P-value = 0.566 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs949056 - rs949054 |
|
GRIK4
|
P-value = 0.972 bet......
P-value = 0.972 between SCZ cases and controls; P-value = 0.767 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs949056 - rs949054 - rs602104 |
|
GRIK4
|
P-value = 0.931 bet......
P-value = 0.931 between SCZ cases and controls; P-value = 0.364 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs949056 - rs949054 - rs602104 - rs2276319 |
|
GRIK4
|
P-value = 0.997 bet......
P-value = 0.997 between SCZ cases and controls; P-value = 0.91 between all cases and controls
More...
|
|
Negative |
Pickard, B. S., 2006 |
|
rs138855 - rs4468 |
|
BRD1
|
|
rs138855 - rs4468 - D22S1169 |
|
BRD1
|
|
rs138855 - rs4468 - D22S1169 - D22S922 |
|
BRD1
|
|
rs138881 - rs138880 |
|
BRD1
|
|
rs138881 - rs138880 - rs2239848 |
|
BRD1
|
|
rs2239848 - rs138855 |
|
BRD1
|
|
rs4468 - D22S1169 - D22S922 |
|
BRD1
|
|
D22S922 - rs132234 |
|
FAM19A5
|
|
rs916005 - rs715519 |
|
MAPK8IP2
|
|
rs715519 - rs2272843 |
|
MAPK8IP2
MOV10L1
|
|
rs715519 - rs2272843 - rs3810971 |
|
MAPK8IP2
MOV10L1
|
|
rs715519 - rs2272843 - rs3810971 - rs137932 |
|
MAPK8IP2
MOV10L1
|
|
rs916005 - rs715519 - rs2272843 |
|
MAPK8IP2
MOV10L1
|
|
rs916005 - rs715519 - rs2272843 - rs3810971 |
|
MAPK8IP2
MOV10L1
|
|
rs137931 - rs6010260 |
|
MLC1
|
|
rs137932 - rs137931 |
|
MLC1
|
|
rs137932 - rs137931 - rs6010260 |
|
MLC1
|
|
rs137931 - rs6010260 - rs138881 |
|
MLC1
BRD1
|
|
rs137931 - rs6010260 - rs138881 - rs138880 |
|
MLC1
BRD1
|
|
rs137932 - rs137931 - rs6010260 - rs138881 |
|
MLC1
BRD1
|
|
rs6010260 - rs138881 |
|
MLC1
BRD1
|
|
rs6010260 - rs138881 - rs138880 |
|
MLC1
BRD1
|
|
rs6010260 - rs138881 - rs138880 - rs2239848 |
|
MLC1
BRD1
|
|
rs2272843 - rs3810971 |
|
MOV10L1
|
|
rs2272843 - rs3810971 - rs137932 |
|
MOV10L1
MLC1
|
|
rs2272843 - rs3810971 - rs137932 - rs137931 |
|
MOV10L1
MLC1
|
|
rs3810971 - rs137932 |
|
MOV10L1
MLC1
|
|
rs3810971 - rs137932 - rs137931 |
|
MOV10L1
MLC1
|
|
rs3810971 - rs137932 - rs137931 - rs6010260 |
|
MOV10L1
MLC1
|
|
rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 |
1-1-1-2-2-2-2-1-2 |
FEZ1
|
P-value = 0.575 in ......
P-value = 0.575 in Caucasians; P-value = 0.391 in African Americans
More...
|
No association was ......
No association was found in either population between specific haplotypes and any of the psychiatric disorders.
More...
|
Negative |
Hodgkinson, C. A., 2007 |
|
rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 |
1-2-2-1-2-2-2-1-2 |
FEZ1
|
P-value = 0.375 in ......
P-value = 0.375 in Caucasians; P-value = 0.161 in African Americans
More...
|
No association was ......
No association was found in either population between specific haplotypes and any of the psychiatric disorders.
More...
|
Negative |
Hodgkinson, C. A., 2007 |
|
rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 |
1-2-2-1-2-1-1-1-2 |
FEZ1
|
P-value = 0.460 in ......
P-value = 0.460 in Caucasians; P-value = 0.713 in African Americans
More...
|
No association was ......
No association was found in either population between specific haplotypes and any of the psychiatric disorders.
More...
|
Negative |
Hodgkinson, C. A., 2007 |
|
rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 |
2-2-2-2-2-2-2-1-2 |
FEZ1
|
P-value = 0.414 in ......
P-value = 0.414 in Caucasians; P-value = 0.860 in African Americans
More...
|
No association was ......
No association was found in either population between specific haplotypes and any of the psychiatric disorders.
More...
|
Negative |
Hodgkinson, C. A., 2007 |
|
rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 |
2-2-2-2-2-2-2-2-1 |
FEZ1
|
P-value = 0.913 in ......
P-value = 0.913 in Caucasians; P-value = 0.855 in African Americans
More...
|
No association was ......
No association was found in either population between specific haplotypes and any of the psychiatric disorders.
More...
|
Negative |
Hodgkinson, C. A., 2007 |
|