GO Report

Basic Info

ID	GO:0016020
Name	membrane
Type	cellular component
No. of Genes in BDgene	137
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO: 0016020: membrane	PBA paper	Askland, K.,2009	NIMH	Fisher's exact test	Results given for gene sets with P < 0.01 from the NIMH PBA-CC data

GO related genes in BDgene (count: 137)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
ALG9	ALG9, alpha-1,2-mannosyltransferase	11q23	1(0/1/0)	IDA[19946888]
DPY19L1	dpy-19-like 1 (C. elegans)	7p14.3-p14.2	1(0/0/1)	IDA[19946888]
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1	7q21.12	1(1/0/0)	TAS[3022150]
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	12q24.2-q24.3	1(1/0/0)	IDA[19946888]
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	5q31-q32	5(2/3/0)	IEA
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	3p21.31	1(0/1/0)	IDA[19946888]
GFAP	glial fibrillary acidic protein	17q21	1(1/0/0)	IEA
HLA-B	major histocompatibility complex, class I, B	6p21.3	2(0/1/1)	IDA[19946888]; TAS[3011411]
SNX4	sorting nexin 4	3q21.2	1(0/0/1)	IDA[9819414]
SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	2p15-p13	1(0/1/0)	IDA[19946888]
NRG1	neuregulin 1	8p12	15(10/5/0)	NAS[8096067]
BCR	breakpoint cluster region	22q11	2(1/1/0)	IDA[19946888]
NF1	neurofibromin 1	17q11.2	1(1/0/0)	IDA[19946888]
SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	7q21.11	1(1/0/0)	IEA
NCOR2	nuclear receptor corepressor 2	12q24	1(0/1/0)	IDA[19946888]
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14q32.33	1(1/0/0)	IDA[19946888]
GLT8D1	glycosyltransferase 8 domain containing 1	3p21.1	1(1/0/0)	IDA[19946888]
SLC6A2	solute carrier family 6 (neurotransmitter transporter), member 2	16q12.2	2(0/2/0)	TAS[2008212]
PRKCZ	protein kinase C, zeta	1p36.33-p36.2	1(1/0/0)	TAS[7925449]
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	9q31-q32	1(1/0/0)	IEA
PCNT	pericentrin	21q22.3	1(0/1/0)	IDA[19946888]
RBM23	RNA binding motif protein 23	14q11.1	1(0/1/0)	IDA[19946888]
ADAM18	ADAM metallopeptidase domain 18	8p11.22	1(0/0/1)	TAS[10395895]
BET1	Bet1 golgi vesicular membrane trafficking protein	7q21.1-q22	1(1/0/0)	IDA[19946888]
LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	4q13	1(0/0/1)	IDA[19946888]
TNK2	tyrosine kinase, non-receptor, 2	3q29	1(0/1/0)	IDA[19946888]
DLG2	discs, large homolog 2 (Drosophila)	11q21	3(1/1/1)	ISS
VAMP7	vesicle-associated membrane protein 7	Xq28 and Yq12	2(0/2/0)	IDA[16677249]
GLI2	GLI family zinc finger 2	2q14	1(0/1/0)	IEA
SLC20A1	solute carrier family 20 (phosphate transporter), member 1	2q13	1(0/1/0)	TAS[8041748]
PIK3C3	phosphatidylinositol 3-kinase, catalytic subunit type 3	18q12.3	1(1/0/0)	IDA[19946888]
STK24	serine/threonine kinase 24	13q31.2-q32.3	2(1/1/0)	IEA
PDE4D	phosphodiesterase 4D, cAMP-specific	5q12	1(0/1/0)	IDA[9371713]; IDA[9371713]
CACNB3	calcium channel, voltage-dependent, beta 3 subunit	12q13	1(0/0/1)	IDA[16525042]
MED12	mediator complex subunit 12	Xq13	1(0/1/0)	IDA[19946888]
ALOX12	arachidonate 12-lipoxygenase	17p13.1	2(1/1/0)	IDA[8912711]
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	1p36	1(0/0/1)	IDA[11853878]
CHRNA10	cholinergic receptor, nicotinic, alpha 10 (neuronal)	11p15.5	1(0/1/0)	TAS[11350119]
PLEKHA5	pleckstrin homology domain containing, family A member 5	12p12	1(1/0/0)	IDA[19946888]
EGFR	epidermal growth factor receptor	7p12	1(0/0/1)	IDA[12435727]
PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	7q22	1(0/0/1)	IDA[12507995]
LMLN	leishmanolysin-like (metallopeptidase M8 family)	3q29	1(0/1/0)	IEA
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	16q22	1(1/0/0)	IDA[18752060]
LSG1	large 60S subunit nuclear export GTPase 1	3q29	1(0/1/0)	IDA[19946888]
PI4K2B	phosphatidylinositol 4-kinase type 2 beta	4p15.31	1(0/1/0)	IDA[19946888]
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	11p13-p12	1(1/0/0)	TAS[7521911]
RYR2	ryanodine receptor 2 (cardiac)	1q43	1(1/0/0)	IDA[12443530]
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha	17q24.2	1(1/0/0)	IDA[19946888]
DRD4	dopamine receptor D4	11p15.5	13(1/12/0)	IDA[7512953]
FGFR2	fibroblast growth factor receptor 2	10q25.3-q26	2(1/1/0)	NAS[8676562]
IL2RB	interleukin 2 receptor, beta	22q13	2(1/1/0)	IDA[19946888]
TIAM2	T-cell lymphoma invasion and metastasis 2	6q25	1(1/0/0)	IEA
RUVBL2	RuvB-like AAA ATPase 2	19q13.3	1(1/0/0)	IEA
TFRC	transferrin receptor	3q29	1(0/1/0)	NAS[1871153]
DAB1	Dab, reelin signal transducer, homolog 1 (Drosophila)	1p32-p31	1(0/1/0)	IEA
SIGLEC6	sialic acid binding Ig-like lectin 6	19q13.3	1(1/0/0)	TAS[9465907]
OSBP2	oxysterol binding protein 2	22q12.2	1(0/1/0)	IEA
PREP	prolyl endopeptidase	6q22	2(2/0/0)	IDA[19946888]
EXOC4	exocyst complex component 4	7q31	1(0/0/1)	IDA[19946888]
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	14q24	2(1/1/0)	IDA[19946888]
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14q32.31	1(0/1/0)	IDA[19946888]
ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	1p13	1(1/0/0)	TAS[1975705]
ADCY8	adenylate cyclase 8 (brain)	8q24	4(2/1/1)	TAS[8163524]
CHRNA4	cholinergic receptor, nicotinic, alpha 4 (neuronal)	20q13.33	1(1/0/0)	ISS
DPP10	dipeptidyl-peptidase 10 (non-functional)	2q14.1	3(2/1/0)	IDA[12662155]
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	22q13.1	2(1/1/0)	IEA
DDX55	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55	12q24.31	1(1/0/0)	IDA[19946888]
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	14q11.2	1(0/1/0)	IDA[16210410]
CIT	citron rho-interacting serine/threonine kinase	12q24.23	2(1/1/0)	IDA[19946888]
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	9q34	3(1/2/0)	TAS[3443096]
P2RX7	purinergic receptor P2X, ligand gated ion channel, 7	12q24	9(2/7/0)	IDA[17785580]
SORCS2	sortilin-related VPS10 domain containing receptor 2	4p16.1	5(3/2/0)	NAS[11499680]
ADCY2	adenylate cyclase 2 (brain)	5p15.3	2(1/1/0)	ISS
DPYSL2	dihydropyrimidinase-like 2	8p22-p21	2(1/0/1)	IDA[20801876]
ARHGAP15	Rho GTPase activating protein 15	2q22.2-q22.3	1(0/1/0)	IEA
TPST2	tyrosylprotein sulfotransferase 2	22q12.1	2(1/0/1)	TAS[9736702]
HPS4	Hermansky-Pudlak syndrome 4	22q12.1	1(1/0/0)	IDA[12756248]
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	2(2/0/0)	ISS
DOCK9	dedicator of cytokinesis 9	13q32.3	1(1/0/0)	IDA[19946888]
PTRH2	peptidyl-tRNA hydrolase 2	17q23.2	1(0/0/1)	IDA[19946888]
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9q33.3	1(0/1/0)	IDA[19946888]
MTMR3	myotubularin related protein 3	22q12.2	1(0/1/0)	IDA[10733931]
SEC63	SEC63 homolog (S. cerevisiae)	6q21	1(1/0/0)	IDA[22375059]
TOM1	target of myb1 (chicken)	22q13.1	1(1/0/0)	IDA[14613930]
ESR1	estrogen receptor 1	6q24-q27	1(0/1/0)	NAS[11960618]
BCL2	B-cell CLL/lymphoma 2	18q21.3	2(0/2/0)	IDA[7896880]
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	2q21.2	2(0/2/0)	IDA[19946888]
NCAM1	neural cell adhesion molecule 1	11q23.2	3(2/1/0)	IDA[19946888]
PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	22q11.21	3(1/2/0)	IDA[19946888]
APOE	apolipoprotein E	19q13.31	1(1/0/0)	IDA[19946888]
GNAS	GNAS complex locus	20q13.2-q13.3	1(0/1/0)	IDA[12719376]; ISS
HLA-A	major histocompatibility complex, class I, A	6p21.3	1(0/1/0)	IDA[19946888]
NUF2	NUF2, NDC80 kinetochore complex component	1q23.3	1(1/0/0)	IDA[19946888]
FOXO3	forkhead box O3	6q21	1(1/0/0)	IEA
P2RX4	purinergic receptor P2X, ligand gated ion channel, 4	12q24.32	1(0/1/0)	IDA[17785580]
CHRM1	cholinergic receptor, muscarinic 1	11q12-q13	1(0/1/0)	TAS[7925360]
COMT	catechol-O-methyltransferase	22q11.21	28(14/14/0)	IDA[19946888]
SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	9p24	1(1/0/0)	TAS[7521911]
FKBP5	FK506 binding protein 5	6p21.31	5(1/4/0)	IDA[19946888]
MUC4	mucin 4, cell surface associated	3q29	2(0/2/0)	NAS[10920259]
PIK3C2A	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	11p15.5-p14	1(0/1/0)	IDA[19946888]
OPA1	optic atrophy 1 (autosomal dominant)	3q29	1(0/1/0)	IDA[19946888]
ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	8q24.22	4(3/0/1)	IDA[19946888]
PLD1	phospholipase D1, phosphatidylcholine-specific	3q26	1(1/0/0)	IDA[19946888]
CRBN	cereblon	3p26.3	1(1/0/0)	IEA
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7p22	1(1/0/0)	ISS
PDLIM5	PDZ and LIM domain 5	4q22	5(4/1/0)	ISS
DSCAM	Down syndrome cell adhesion molecule	21q22.2-q22.3	3(1/2/0)	TAS[9426258]
SLC18A2	solute carrier family 18 (vesicular monoamine transporter), member 2	10q25	1(1/0/0)	TAS[8095030]
CD36	CD36 molecule (thrombospondin receptor)	7q11.2	3(2/1/0)	TAS[2468669]
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	3p21.1	2(2/0/0)	IDA[19946888]
ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	3q29	1(0/1/0)	IDA[19946888]
NCAPD3	non-SMC condensin II complex, subunit D3	11q25	1(1/0/0)	IDA[19946888]
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	17p13.1	1(1/0/0)	IDA[16677249]
HLA-G	major histocompatibility complex, class I, G	6p21.3	1(1/0/0)	IDA[19946888]
ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	12q24.11	2(0/2/0)	IDA[22375059]
MYH14	myosin, heavy chain 14, non-muscle	19q13.33	1(0/1/0)	IDA[19946888]
COBL	cordon-bleu WH2 repeat protein	7p12.2-p12.1	1(1/0/0)	ISS
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8q24.1-q24.2	1(0/1/0)	IEA
MED15	mediator complex subunit 15	22q11.2	1(0/1/0)	IDA[19946888]
CLTC	clathrin, heavy chain (Hc)	17q23.1	1(0/0/1)	IDA[16210410]
SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5q33.3	1(0/0/1)	IDA[19946888]
NPHP4	nephronophthisis 4	1p36	1(1/0/0)	IC[12006559]
MsrA	methionine sulfoxide reductase A	8p23.1	1(1/0/0)	IEA
CHN2	chimerin 2	7p15.3	1(1/0/0)	IEA
GRIN3A	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	9q31.1	1(0/1/0)	IDA[17997397]
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	5q13.1	1(1/0/0)	IDA[19946888]
NDE1	nudE neurodevelopment protein 1	16p13.11	1(1/0/0)	IDA[19946888]
KIF5B	kinesin family member 5B	10p11.22	1(0/0/1)	IDA[19946888]
ZDHHC13	zinc finger, DHHC-type containing 13	11p15.1	1(0/0/1)	IDA[19946888]
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	17p13.3	1(0/1/0)	IDA[19946888]
DIO2	deiodinase, iodothyronine, type II	14q24.2-q24.3	1(1/0/0)	IC[9837913]
NUP107	nucleoporin 107kDa	12q14	1(1/0/0)	IDA[19946888]
LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	1p32.3	1(1/0/0)	IDA[19946888]
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	5p15.2	1(1/0/0)	ISS
HTR4	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	5q31-q33	2(1/1/0)	IDA[16102731]
SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	13q32.3	1(0/1/0)	TAS[7896779]