Gene Report

Approved Symbol	SORCS2
Symbol Alias	KIAA1329
Approved Name	sortilin-related VPS10 domain containing receptor 2
Location	4p16.1
Position	chr4:7192538-7742836, 1
External Links	HGNC: 16698 Entrez Gene: 57537 Ensembl: ENSG00000184985 UCSC: uc003gkb.4
No. of Studies	5 (Positive: 3; Negative: 2; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs4292336	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study
Takata, A.,2011(a)	SNP: rs10937823, rs11734984, rs11736984, rs12645507, rs13139074, rs16840892, rs34058821, rs4411993	In the association analysis using Japanese samples, a SNP in SORCS2 (rs10937823) showed nominal genotypic association.	Positive	Comment on Study
Ollila, H. M.,2009	SNP: rs10937823, rs4411993, rs7683874	we could confirm findings for this association with BPI.	Positive	Comment on Study
Yosifova, A.,2009	SNP: rs4411993	No SNP of this gene had significant association with BD in our population.	Negative	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0016. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Region: chr4:7192538..7742836 View in gBrowse