Gene Report

Basic Info
Approved Symbol HLA-G
Approved Name major histocompatibility complex, class I, G
Previous Name HLA-G histocompatibility antigen, class I, G
Name Alias b2 microglobulin
Location 6p21.3
Position chr6:29826967-29831125, 1
External Links HGNC: 4964
Entrez Gene: 3135
Ensembl: ENSG00000204632
UCSC: uc003nnw.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Debnath, M.,2012 Other variant: rs66554220 The analysis of the HLA-G 14bp genotype distribution revealed that the homozygous state of 14bp Ins allele was significantly more prevalent in healthy controls than in BD patients. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 29)

GO terms by PBA (count: 3)

GO terms by database search (count: 26)

Gene related KEGG pathways (count: 7)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 6)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 9)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:29826967..29831125 View in gBrowse
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