Gene Report

Basic Info
Approved Symbol HSPA5
Previous Symbol GRP78
Symbol Alias BiP
Approved Name heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Previous Name heat shock 70kD protein 5 (glucose-regulated protein, 78kD)
Location 9q33.3
Position chr9:125234853-125241330, -1
External Links HGNC: 5238
Entrez Gene: 3309
Ensembl: ENSG00000044574
UCSC: uc004bpn.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Yosifova, A.,2009 SNP: rs1140763, rs12009, rs17840761, rs391957 No SNP of this gene had significant association with BD in our population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 53)

GO terms by PBA (count: 5)

GO terms by database search (count: 48)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 34)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 4)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr9:125234853..125241330 View in gBrowse
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