Gene Report

Basic Info
Approved Symbol GLI2
Symbol Alias THP2, HPE9, THP1
Approved Name GLI family zinc finger 2
Previous Name GLI-Kruppel family member GLI2, "glioma-associated oncogene family zinc finger 2"
Name Alias tax-responsive element-2 holding protein, "tax helper protein 1", "tax helper protein 2"
Location 2q14
Position chr2:120735623-120992653, 1
External Links HGNC: 4318
Entrez Gene: 2736
Ensembl: ENSG00000074047
UCSC: uc010flp.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gonzalez, S., 2014 SNP: rs1880542
Other variant: GLI2_Chr2:121444612, GLI2_Chr2:121464518
The associated SNP in this gene showed no significant association with BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 65)

GO terms by PBA (count: 5)

GO terms by database search (count: 60)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:120735623..120992653 View in gBrowse
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