Gene Report

Basic Info
Approved Symbol MTOR
Previous Symbol FRAP, FRAP2, FRAP1
Symbol Alias RAFT1, RAPT1, FLJ44809
Approved Name mechanistic target of rapamycin (serine/threonine kinase)
Previous Name FK506 binding protein 12-rapamycin associated protein 1
Name Alias FK506 binding protein 12-rapamycin associated protein 2, "rapamycin target protein", "FKBP12-rapamycin complex-associated protein 1", "FKBP-rapamycin associated protein", "rapamycin associated protein FRAP2", "dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)", "rapamycin and FKBP12 target 1", "mammalian target of rapamycin"
Location 1p36
Position chr1:11106535-11262507, -1
External Links HGNC: 3942
Entrez Gene: 2475
Ensembl: ENSG00000198793
UCSC: uc001asd.3
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Cruceanu, C., 2013 Other variant: MTOR_Chr1:11194520_C/T Rare variant was found within this gene. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 84)

GO terms by PBA (count: 6)

GO terms by database search (count: 78)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 22)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:11106535..11262507 View in gBrowse
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