BDgene

Gene Report

Basic Info
Approved Symbol CHRM1
Approved Name cholinergic receptor, muscarinic 1
Name Alias acetylcholine receptor, muscarinic 1
Location 11q12-q13
Position chr11:62908679-62921807, -1
External Links HGNC: 1950
Entrez Gene: 1128
Ensembl: ENSG00000168539
UCSC: uc001nwi.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2007 SNP: rs1938677, rs2507821, rs4963323 no evidence of interaction among these 19 cholinergic genes was found by Allelic Association, Haploview Tests, FITF analysis and FDR correction Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 32)

GO terms by PBA (count: 6)

GO terms by database search (count: 26)


Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)


Gene related BioCarta pathways (count: 4)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 4)


Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 3)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

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Region: chr11:62908679..62921807 View in gBrowse
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