Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	DDX55
Symbol Alias	KIAA1595
Approved Name	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Location	12q24.31
Position	chr12:123602077-123620941, 1
External Links	HGNC: 20085 Entrez Gene: 57696 Ensembl: ENSG00000111364 UCSC: uc001ufi.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Shink, E.,2005(a)	Other variant: KIAA1595_GC29E04A, KIAA1595_GC29E08A, KIAA1595_GC29E06A	We found polymorphisms associated with bipolar disorder in this gene.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016020	membrane	cellular component	IDA[19946888]	137

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005524	ATP binding	molecular function	IEA	118
GO:0004386	helicase activity	molecular function	IEA	4
GO:0044822	poly(A) RNA binding	molecular function	IDA[22658674]	44
GO:0008152	metabolic process	biological process	IEA	50
GO:0005515	protein binding	molecular function	IPI[25416956]	563

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in BDgene	Brief Description
hsa00790	Folate biosynthesis	7
hsa00500	Starch and sucrose metabolism	5

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 3)

Variant Name	Variant Type	No. of Studies (Positive/Negative/Trend)
KIAA1595_GC29E04A	point mutation	1 (0/1/0)
KIAA1595_GC29E06A	point mutation	1 (1/0/0)
KIAA1595_GC29E08A	point mutation	1 (0/1/0)

Gene related regions (count: 6)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
12q24.3	chr12:120300000-133275309	1 (1/0/0)
Chr 12	chr12:0-133275309	3 (0/3/0)
12q24	chr12:108600000-133275309	4 (1/1/2)
12q23-q24	chr12:95800000-133275309	3 (2/0/1)
12q24.31	chr12:120300000-125400000	1 (1/0/0)
12q	chr12:38200000-133851895	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr12:123602077..123620941 View in gBrowse