Gene Report

Basic Info
Approved Symbol ATP1A1
Approved Name ATPase, Na+/K+ transporting, alpha 1 polypeptide
Name Alias sodium/potassium-transporting ATPase subunit alpha-1, "sodium pump subunit alpha-1", "sodium-potassium ATPase catalytic subunit alpha-1"
Location 1p13
Position chr1:116372668-116410261, 1
External Links HGNC: 799
Entrez Gene: 476
Ensembl: ENSG00000163399
UCSC: uc010oww.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Goldstein, I.,2009 SNP: rs1016732, rs11805078, rs2854248 In summary, this study demonstrates for the first time that genetic variations in tagging SNPs in the three genes of isoforms of Na<sup>+</sup , K<sup>+</sup> -ATPase are associated with BD and suggest the role of this enzyme in the etiology of BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 55)

GO terms by PBA (count: 5)

GO terms by database search (count: 50)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 10)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 3)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:116372668..116410261 View in gBrowse
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