Gene Report

Basic Info
Approved Symbol HSP90AA1
Previous Symbol HSPC1, HSPCA
Symbol Alias Hsp89, Hsp90, FLJ31884, HSP90N
Approved Name heat shock protein 90kDa alpha (cytosolic), class A member 1
Previous Name heat shock 90kD protein 1, alpha, "heat shock 90kDa protein 1, alpha"
Location 14q32.33
Position chr14:102080738-102139699, -1
External Links HGNC: 5253
Entrez Gene: 3320
Ensembl: ENSG00000080824
UCSC: uc001ykv.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Drago, A., 2016 Freq(Significant SNPs/total SNPs%)=0.03. Encodes for a is stress induced molecular chaperonen that functions as homodimer. Promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 42)

GO terms by PBA (count: 5)

GO terms by database search (count: 37)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 8)

Gene related interactors from protein-protein interactions data in HPRD (count: 75)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:102080738..102139699 View in gBrowse
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