Gene Report

Basic Info
Approved Symbol GNAI2
Previous Symbol GNAI2B
Symbol Alias GIP
Approved Name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Name Alias GTP-binding regulatory protein Gi alpha-2 chain
Location 3p21.31
Position chr3:50226292-50259355, 1
External Links HGNC: 4385
Entrez Gene: 2771
Ensembl: ENSG00000114353
UCSC: uc003cyq.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
McDonald, M. L.,2012 SNP: rs2282751 None of the association tests of the tagSNPs with either BPD I or BPD II reached genome-wide significance (P < 5E-08). Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 38)

GO terms by PBA (count: 5)

GO terms by database search (count: 33)

Gene related KEGG pathways (count: 6)

KEGG pathways by PBA (count: 3)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 42)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:50226292..50259355 View in gBrowse
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