Gene Report

Basic Info
Approved Symbol SIGLEC6
Previous Symbol CD33L, CD33L1
Symbol Alias OB-BP1, SIGLEC-6, CD327
Approved Name sialic acid binding Ig-like lectin 6
Location 19q13.3
Position chr19:51519525-51531856, -1
External Links HGNC: 10875
Entrez Gene: 946
Ensembl: ENSG00000105492
UCSC: uc002pwy.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.00069, Product of P truncation <=0.01=0.00211, Product of P truncation <=0.001=0.00087. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 7)

GO terms by PBA (count: 4)

GO terms by database search (count: 3)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

View in gBrowse

Region: chr19:51519525..51531856 View in gBrowse
View in gBrowse