Gene Report

Basic Info
Approved Symbol OPA1
Symbol Alias NTG, KIAA0567, FLJ12460, NPG, MGM1
Approved Name optic atrophy 1 (autosomal dominant)
Name Alias mitochondrial dynamin-like GTPase, "dynamin-like guanosine triphosphatase", "Dynamin-like 120 kDa protein, mitochondrial"
Location 3q29
Position chr3:193593144-193697823, 1
External Links HGNC: 8140
Entrez Gene: 4976
Ensembl: ENSG00000198836
UCSC: uc003ftg.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Schosser, A.,2011 No significant association was observed. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 27)

GO terms by PBA (count: 2)

GO terms by database search (count: 25)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 50)

Literature-origin SNPs (count: 1)

LD-proxies (count: 49)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:193593144..193697823 View in gBrowse
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