BDgene

Gene Report

Basic Info
Approved Symbol DDX18
Symbol Alias MrDb
Approved Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Previous Name DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)
Location 2q21.2
Position chr2:117814650-117832379, 1
External Links HGNC: 2741
Entrez Gene: 8886
Ensembl: ENSG00000088205
UCSC: uc002tlh.1
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Djurovic, S.,2010 SNP: rs12052834, rs1472779, rs4257412 No significant association of this gene was observed in BD. Negative Comment on Study
Gonzalez, S., 2014 SNP: rs1516003 The associated SNP in this gene showed no significant association with BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 7)

GO terms by PBA (count: 1)

GO terms by database search (count: 6)


Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 4)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr2:117814650..117832379 View in gBrowse
View in gBrowse