Gene Report

Basic Info
Approved Symbol PDE4D
Previous Symbol DPDE3
Approved Name phosphodiesterase 4D, cAMP-specific
Previous Name phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3)
Name Alias phosphodiesterase E3 dunce homolog (Drosophila)
Location 5q12
Position chr5:58969038-60522120, -1
External Links HGNC: 8783
Entrez Gene: 5144
Ensembl: ENSG00000113448
UCSC: uc003jsa.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
McDonald, M. L.,2012 SNP: rs17741863 None of the association tests of the tagSNPs with either BPD I or BPD II reached genome-wide significance (P < 5E-08). Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 53)

GO terms by PBA (count: 4)

GO terms by database search (count: 49)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 15)

Literature-origin SNPs (count: 1)

LD-proxies (count: 14)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr5:58969038..60522120 View in gBrowse
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