Gene Report

Basic Info
Approved Symbol DPP10
Symbol Alias DPRP3
Approved Name dipeptidyl-peptidase 10 (non-functional)
Previous Name dipeptidylpeptidase 10, "dipeptidyl-peptidase 10"
Location 2q14.1
Position chr2:114442299-115845752, 1
External Links HGNC: 20823
Entrez Gene: 57628
Ensembl: ENSG00000175497
UCSC: uc002tle.3
No. of Studies 3 (Positive: 2; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 3)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gonzalez, S., 2014 SNP: rs1847694, rs10180987
Other variant: DPP10_Chr2:116251310, DPP10_Chr2:116314867
Significant association of SNP in this gene with BD was observed. Positive Comment on Study
Ollila, H. M.,2009 SNP: rs1375144 It showed no evidence for association with BPI in our study. Negative Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.00032, Product of P truncation <=0.01=0.00019, Product of P truncation <=0.001=0.00011. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 4)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 46)

Literature-origin SNPs (count: 6)

LD-proxies (count: 40)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr2:114442299..115845752 View in gBrowse
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