Gene Report

Basic Info
Approved Symbol HLA-B
Previous Symbol AS
Approved Name major histocompatibility complex, class I, B
Previous Name ankylosing spondylitis
Location 6p21.3
Position chr6:31353872-31357188, -1
External Links HGNC: 4932
Entrez Gene: 3106
Ensembl: ENSG00000234745
UCSC: uc011gwy.2
No. of Studies 2 (Positive: 0; Negative: 1; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ross, K. A.,2011 SNP: rs9378249 Suggestive association was found at rs9378249. Trend Comment on Study
Jun, T. Y.,2002 Other variant: HLA-B_polymorphism The results of the present study suggest that HLA alleles may not confer susceptibility to bipolar disorder in the Korean population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 38)

GO terms by PBA (count: 6)

GO terms by database search (count: 32)

Gene related KEGG pathways (count: 7)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 6)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 13)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:31353872..31357188 View in gBrowse
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