Gene Report

Basic Info
Approved Symbol GFAP
Symbol Alias FLJ45472
Approved Name glial fibrillary acidic protein
Name Alias intermediate filament protein
Location 17q21
Position chr17:44905008-44916937, -1
External Links HGNC: 4235
Entrez Gene: 2670
Ensembl: ENSG00000131095
UCSC: uc002ihq.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ament, S. A., 2015 P-value=0.0044, OR=11.8. No individual gene had a significant burden of segregating rare variants in BD pedigrees after correcting for multiple tests, although several genes had suggestive trends. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 20)

GO terms by PBA (count: 1)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 19)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 2)

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Region: chr17:44905008..44916937 View in gBrowse
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