BDgene

Gene Report

Basic Info
Approved Symbol SEMA3D
Symbol Alias coll-2, Sema-Z2
Approved Name sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
Location 7q21.11
Position chr7:84995553-85186855, -1
External Links HGNC: 10726
Entrez Gene: 223117
Ensembl: ENSG00000153993
UCSC: uc003uic.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kuo, P. H., 2014 SNP: rs10260011 Gene-based P-value (allelic model) =0.0419, P-value (additive model) =0.0368. SEMA3D, with a P-value of less than 0.05 (P= 0.037). Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 5)

GO terms by PBA (count: 4)

GO terms by database search (count: 1)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

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Region: chr7:84995553..85186855 View in gBrowse
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