BDgene

Gene Report

Basic Info
Approved Symbol EGFR
Previous Symbol ERBB
Symbol Alias ERBB1
Approved Name epidermal growth factor receptor
Previous Name epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
Name Alias erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian), "erb-b2 receptor tyrosine kinase 1"
Location 7p12
Position chr7:55019021-55211628, 1
External Links HGNC: 3236
Entrez Gene: 1956
Ensembl: ENSG00000146648
UCSC: uc003tqk.3
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Sklar, P., 2008 SNP: rs17172438, rs729969 Haplotype analysis further supported single SNP results highlighting EGFR (P-value = 8.36E-08) Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 120)

GO terms by PBA (count: 10)

GO terms by database search (count: 110)


Gene related KEGG pathways (count: 18)

Gene related BioCarta pathways (count: 15)

Gene related interactors from protein-protein interactions data in HPRD (count: 155)

Related other genetic factors
Gene related SNPs (count: 18)

Literature-origin SNPs (count: 2)

LD-proxies (count: 16)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 2)


Gene relationship with MDD

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Region: chr7:55019021..55211628 View in gBrowse
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