Gene Report

Basic Info
Approved Symbol ADCY2
Symbol Alias HBAC2, KIAA1060, AC2
Approved Name adenylate cyclase 2 (brain)
Location 5p15.3
Position chr5:7396208-7830081, 1
External Links HGNC: 233
Entrez Gene: 108
Ensembl: ENSG00000078295
UCSC: uc003jdz.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs12186377, rs12189243, rs2973331, rs4289537, rs6878196 A number of genes with no previous association to BD have multiple SNPs with suggestive association, including the brain-expressed gene ADCY2. Negative Comment on Study
Muhleisen, T. W., 2014 SNP: rs17826816 As the third most significant finding in our study Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 34)

GO terms by PBA (count: 5)

GO terms by database search (count: 29)

Gene related KEGG pathways (count: 5)

KEGG pathways by PBA (count: 3)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 36)

Literature-origin SNPs (count: 6)

LD-proxies (count: 30)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:7396208..7830081 View in gBrowse
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