Gene Report

Basic Info
Approved Symbol TPST2
Symbol Alias TANGO13B
Approved Name tyrosylprotein sulfotransferase 2
Name Alias transport and golgi organization 13 homolog B (Drosophila)
Location 22q12.1
Position chr22:26521983-26596717, -1
External Links HGNC: 12021
Entrez Gene: 8459
Ensembl: ENSG00000128294
UCSC: uc003acx.3
No. of Studies 2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Georgi, B., 2014 SNP: rs117701840 Amish-specific putative damaging exonic missense variant was found within this gene. Trend Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0077. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 2)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr22:26521983..26596717 View in gBrowse
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