Gene Report

Basic Info
Approved Symbol STK24
Symbol Alias MST-3, MST3, MST3B, STK3, STE20
Approved Name serine/threonine kinase 24
Previous Name serine/threonine kinase 24 (Ste20, yeast homolog)
Name Alias STE20-like kinase 3, "sterile 20-like kinase 3"
Location 13q31.2-q32.3
Position chr13:98445185-98577940, -1
External Links HGNC: 11403
Entrez Gene: 8428
Ensembl: ENSG00000102572
UCSC: uc001vnn.2
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0011. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Yosifova, A.,2009 SNP: rs3783006, rs7324994, rs9517312, rs9517313, rs9517328, rs9556964 No SNP of this gene had significant association with BD in our population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 24)

GO terms by PBA (count: 4)

GO terms by database search (count: 20)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 24)

Literature-origin SNPs (count: 6)

LD-proxies (count: 18)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr13:98445185..98577940 View in gBrowse
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