BDgene

GO Report

Basic Info
ID GO:0044281
Name small molecule metabolic process
Type biological process
No. of Genes in BDgene  117
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 117)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
NNMT nicotinamide N-methyltransferase 11q23.1 1(1/0/0) TAS
INS insulin 11p15.5 1(0/1/0) TAS
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 2p14-p12 1(1/0/0) TAS
ACSM1 acyl-CoA synthetase medium-chain family member 1 16p12.3 1(0/0/1) TAS
ADCY9 adenylate cyclase 9 16p13.3 2(1/1/0) TAS
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18p11.22 6(5/1/0) TAS
GPC5 glypican 5 13q32 1(0/0/1) TAS
AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.33 3(3/0/0) TAS
ADSL adenylosuccinate lyase 22q13.1 2(1/1/0) TAS
CD36 CD36 molecule (thrombospondin receptor) 7q11.2 3(2/1/0) TAS
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1q24.1 1(0/1/0) TAS
PRODH proline dehydrogenase (oxidase) 1 22q11.2 4(0/4/0) TAS
APOE apolipoprotein E 19q13.31 1(1/0/0) TAS
CHRM3 cholinergic receptor, muscarinic 3 1q43 1(0/1/0) TAS
NCOR2 nuclear receptor corepressor 2 12q24 1(0/1/0) TAS
ADRA2A adrenoceptor alpha 2A 10q25.2 1(0/1/0) TAS
FIG4 FIG4 phosphoinositide 5-phosphatase 6q21 1(1/0/0) TAS
NOS3 nitric oxide synthase 3 (endothelial cell) 7q36 2(1/1/0) TAS
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 5p15.31 1(1/0/0) TAS
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 21q22.3 1(0/1/0) TAS
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 7q21.12 1(1/0/0) TAS
UPP1 uridine phosphorylase 1 7p12.3 1(1/0/0) TAS
TPH2 tryptophan hydroxylase 2 12q15 13(10/3/0) TAS
TBXAS1 thromboxane A synthase 1 (platelet) 7q34-q35 1(0/1/0) TAS
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 10p12.2 4(1/3/0) TAS
GSTZ1 glutathione S-transferase zeta 1 14q24.3 1(1/0/0) TAS
PLD1 phospholipase D1, phosphatidylcholine-specific 3q26 1(1/0/0) TAS
NUP107 nucleoporin 107kDa 12q14 1(1/0/0) TAS
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 14q13.3 1(0/0/1) TAS
ADSSL1 adenylosuccinate synthase like 1 14q32.33 1(0/1/0) TAS
MPC2 mitochondrial pyruvate carrier 2 1q24 1(0/1/0) TAS
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 8p22 1(0/1/0) TAS
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 2q11.2 1(0/0/1) TAS
MTMR3 myotubularin related protein 3 22q12.2 1(0/1/0) TAS
GSS glutathione synthetase 20q11.2 1(0/0/1) TAS
DIO2 deiodinase, iodothyronine, type II 14q24.2-q24.3 1(1/0/0) TAS
GCLC glutamate-cysteine ligase, catalytic subunit 6p12 1(0/1/0) TAS
TH tyrosine hydroxylase 11p15.5 16(4/12/0) TAS
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 9q22.31 1(0/1/0) TAS
CHAT choline O-acetyltransferase 10q11.2 1(0/1/0) TAS
CROT carnitine O-octanoyltransferase 7q21.1 1(0/0/1) TAS
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 Xq26.2 1(0/0/1) TAS
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 5q33.1 1(1/0/0) TAS
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 16q24.1 1(0/1/0) TAS
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(1/0/0) TAS
NAMPT nicotinamide phosphoribosyltransferase 7q22.3 1(1/0/0) TAS
NUP214 nucleoporin 214kDa 9q34 1(0/1/0) TAS
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 17p12 1(1/0/0) TAS
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 1(1/0/0) TAS
OXCT1 3-oxoacid CoA transferase 1 5p13 1(1/0/0) TAS
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 2(2/0/0) TAS
INPP1 inositol polyphosphate-1-phosphatase 2q32 1(0/1/0) TAS
GCH1 GTP cyclohydrolase 1 14q22.1-q22.2 2(1/1/0) TAS
TPH1 tryptophan hydroxylase 1 11p15.3-p14 14(5/9/0) TAS
PLCG1 phospholipase C, gamma 1 20q12-q13.1 1(0/1/0) TAS
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 3(1/2/0) TAS
ASMT acetylserotonin O-methyltransferase Xp22.3 and Yp11.3 1(1/0/0) TAS
MAOB monoamine oxidase B Xp11.4-p11.3 4(2/2/0) TAS
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 12p13 2(1/1/0) TAS
CREBBP CREB binding protein 16p13.3 1(0/1/0) TAS
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 11q11-q12 1(1/0/0) TAS
SYNJ1 synaptojanin 1 21q22.2 2(0/2/0) TAS
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 22q13.1 2(1/1/0) TAS
CERS3 ceramide synthase 3 15q26.3 1(0/0/1) TAS
NQO1 NAD(P)H dehydrogenase, quinone 1 16q12-q22 1(0/1/0) TAS
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 8q24.22 4(3/0/1) TAS
PI4K2B phosphatidylinositol 4-kinase type 2 beta 4p15.31 1(0/1/0) TAS
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1p36.3 16(10/6/0) TAS
LPIN1 lipin 1 2p25.1 1(0/0/1) TAS
QDPR quinoid dihydropteridine reductase 4p15.31 1(1/0/0) TAS
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3q29 2(1/1/0) TAS
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 1(1/0/0) TAS
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 18p11.2 4(2/2/0) TAS
ADRA2C adrenoceptor alpha 2C 4p16.3 1(0/1/0) TAS
ADCY2 adenylate cyclase 2 (brain) 5p15.3 2(1/1/0) TAS
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 12q24.12 3(3/0/0) TAS
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 5(2/3/0) TAS
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 20(17/3/0) TAS
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1p36.1 1(0/1/0) TAS
GCLM glutamate-cysteine ligase, modifier subunit 1p21 1(0/0/1) TAS
GSTM1 glutathione S-transferase mu 1 1p13.3 1(1/0/0) TAS
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2p23.1 1(0/1/0) TAS
NT5C2 5'-nucleotidase, cytosolic II 10q24.32 2(2/0/0) TAS
AKR1D1 aldo-keto reductase family 1, member D1 7q32-q33 2(0/1/1) TAS
NPAS2 neuronal PAS domain protein 2 2q11.2 5(3/2/0) TAS
NDUFA4 NDUFA4, mitochondrial complex associated 7p21.3 1(0/0/1) TAS
GBE1 glucan (1,4-alpha-), branching enzyme 1 3p12.2 1(0/1/0) TAS
NCAN neurocan 19p12 1(1/0/0) TAS
FAR2 fatty acyl CoA reductase 2 12p11.23 1(0/1/0) TAS
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 8q21.1-q21.3 1(0/1/0) TAS
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 6p21.3 1(1/0/0) TAS
ACAN aggrecan 15q26.1 1(1/0/0) TAS
GSTT1 glutathione S-transferase theta 1 22q11.23 alternate reference locus 1(1/0/0) TAS
COMT catechol-O-methyltransferase 22q11.21 28(14/14/0) TAS
PLA2G1B phospholipase A2, group IB (pancreas) 12q24.31 4(1/3/0) TAS
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 11p15.5-p14 1(0/1/0) TAS
APOB apolipoprotein B 2p24-p23 1(0/0/1) TAS
GNAS GNAS complex locus 20q13.2-q13.3 1(0/1/0) TAS
DAO D-amino-acid oxidase 12q24.11 5(1/4/0) TAS
DIO3 deiodinase, iodothyronine, type III 14q32 1(0/1/0) TAS
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 3p14.3 1(1/0/0) TAS
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 22q11.21 3(1/2/0) TAS
MAOA monoamine oxidase A Xp11.4-p11.3 21(10/11/0) TAS
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 1(0/0/1) TAS
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(1/0/0) TAS
ADCY8 adenylate cyclase 8 (brain) 8q24 4(2/1/1) TAS
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1q42.2 1(1/0/0) TAS
ALOX12 arachidonate 12-lipoxygenase 17p13.1 2(1/1/0) TAS
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 18p11.2 1(1/0/0) TAS
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 14q32.33 1(1/0/0) TAS
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 17q24.2 1(1/0/0) TAS
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1q43 2(1/1/0) TAS
AANAT aralkylamine N-acetyltransferase 17q25.1 2(0/2/0) TAS
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1q25.3 1(1/0/0) TAS
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 18q12.3 1(1/0/0) TAS
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 6p21.1 1(1/0/0) TAS
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 14q24 2(1/1/0) TAS