Gene Report

Basic Info
Approved Symbol PLCG1
Previous Symbol PLC1
Symbol Alias PLC148, PLC-II, PLCgamma1, NCKAP3
Approved Name phospholipase C, gamma 1
Previous Name phospholipase C, gamma 1 (formerly subtype 148)
Location 20q12-q13.1
Position chr20:41136960-41196801, 1
External Links HGNC: 9065
Entrez Gene: 5335
Ensembl: ENSG00000124181
UCSC: uc002xjo.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ftouhi-Paquin, N.,2001 Other variant: PLCG1_exon26_C/T, PLCG1_exon31_G/T, PLCG1_exon9_A/G No significant association was observed in BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 44)

GO terms by PBA (count: 4)

GO terms by database search (count: 40)

Gene related KEGG pathways (count: 13)

Gene related BioCarta pathways (count: 23)

Gene related interactors from protein-protein interactions data in HPRD (count: 89)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 3)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr20:41136960..41196801 View in gBrowse
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