Gene Report

Basic Info
Approved Symbol TBXAS1
Symbol Alias CYP5, CYP5A1, THAS, TXS, TXAS, TS
Approved Name thromboxane A synthase 1 (platelet)
Previous Name thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V)
Name Alias cytochrome P450, family 5, subfamily A, polypeptide 1
Location 7q34-q35
Position chr7:139777051-140020325, 1
External Links HGNC: 11609
Entrez Gene: 6916
Ensembl: ENSG00000059377
UCSC: uc003vvi.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs17161272 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 15)

GO terms by PBA (count: 2)

GO terms by database search (count: 13)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 2)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 2)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr7:139777051..140020325 View in gBrowse
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