Gene Report

Basic Info
Approved Symbol CHRM3
Approved Name cholinergic receptor, muscarinic 3
Name Alias acetylcholine receptor, muscarinic 3
Location 1q43
Position chr1:239386565-239915452, 1
External Links HGNC: 1952
Entrez Gene: 1131
Ensembl: ENSG00000133019
UCSC: uc001hyp.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2007 SNP: rs1019882, rs10495447, rs528011, rs543307, rs621060, rs658842, rs6688537, rs6700643, rs7520974 no evidence of interaction among these 19 cholinergic genes was found by Allelic Association, Haploview Tests, FITF analysis and FDR correction Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 33)

GO terms by PBA (count: 6)

GO terms by database search (count: 27)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 8)

Related other genetic factors
Gene related SNPs (count: 84)

Literature-origin SNPs (count: 9)

LD-proxies (count: 75)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:239386565..239915452 View in gBrowse
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