Gene Report

Basic Info
Approved Symbol MTR
Symbol Alias cblG
Approved Name 5-methyltetrahydrofolate-homocysteine methyltransferase
Location 1q43
Position chr1:236795281-236903981, 1
External Links HGNC: 7468
Entrez Gene: 4548
Ensembl: ENSG00000116984
UCSC: uc001hyi.4
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Yosifova, A.,2009 SNP: rs1805087 No SNP of this gene had significant association with BD in our population. Negative Comment on Study
Kempisty, B., 2007 (b) Other variant: MTR_A2756G MTR 2756AGG or 2756AG genotypes are linked to BDI Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 1)

GO terms by database search (count: 17)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 19)

Literature-origin SNPs (count: 1)

LD-proxies (count: 18)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr1:236795281..236903981 View in gBrowse
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