Gene Report

Basic Info
Approved Symbol GCLC
Previous Symbol GLCLC, GLCL
Symbol Alias GCS
Approved Name glutamate-cysteine ligase, catalytic subunit
Location 6p12
Position chr6:53497341-53616970, -1
External Links HGNC: 4311
Entrez Gene: 2729
Ensembl: ENSG00000001084
UCSC: uc003pbw.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fullerton, J. M.,2010 Other variant: GCLC_5'UTR_repeat No association was detected with the gene encoding GCLC. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 33)

GO terms by PBA (count: 0)

GO terms by database search (count: 33)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:53497341..53616970 View in gBrowse
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