BDgene

Gene Report

Basic Info
Approved Symbol AANAT
Symbol Alias SNAT
Approved Name aralkylamine N-acetyltransferase
Previous Name arylalkylamine N-acetyltransferase
Name Alias serotonin N-acetyltransferase
Location 17q25.1
Position chr17:76453351-76470117, 1
External Links HGNC: 19
Entrez Gene: 15
Ensembl: ENSG00000129673
UCSC: uc002jro.3
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Mansour, H. A.,2009 Gene-based tests:X<sup>2</sup>=1.997, P-value = 0.482 in additive model, X<sup>2</sup>=1.811, P-value = 0.538 in dominant model, X<sup>2</sup>=1.818, P-value = 0.55 in recessive model in BPI. No significant association was observed using neither single SNP-based analyses nor gene-based tests in BPI. Negative Comment on Study
Byrne, E. M., 2014 P-value=0.71. Gene-based tests show no significant association between this gene and BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 21)

GO terms by PBA (count: 0)

GO terms by database search (count: 21)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 1)


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Region: chr17:76453351..76470117 View in gBrowse
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