Gene Report

Basic Info
Approved Symbol NQO1
Previous Symbol NMOR1, DIA4
Symbol Alias DHQU, QR1, DTD
Approved Name NAD(P)H dehydrogenase, quinone 1
Previous Name diaphorase (NADH/NADPH) (cytochrome b-5 reductase)
Location 16q12-q22
Position chr16:69706996-69726951, -1
External Links HGNC: 2874
Entrez Gene: 1728
Ensembl: ENSG00000181019
UCSC: uc002exp.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Pae, C. U., 2007 (b) Other variant: NQO1_C609T The NQO1 gene polymorphism was not related to a susceptibility to mood disorders (BD and MDD). Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 25)

GO terms by PBA (count: 0)

GO terms by database search (count: 25)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr16:69706996..69726951 View in gBrowse
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