Gene Report

Basic Info
Approved Symbol GSS
Approved Name glutathione synthetase
Location 20q11.2
Position chr20:34928430-34955817, -1
External Links HGNC: 4624
Entrez Gene: 2937
Ensembl: ENSG00000100983
UCSC: uc002xbg.3
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Green, E. K.,2012 SNP: rs2273684 BD ImmunoChip:P-value = 0.00000923,OR = 1.245;ImmunoChip, PGC-BD combined data:P-balue = 0.000000472,OR = 1.119 Suggestive association was found. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 20)

GO terms by PBA (count: 1)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 4)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 4)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 1)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

View in gBrowse

Region: chr20:34928430..34955817 View in gBrowse
View in gBrowse