BDgene

Gene Report

Basic Info
Approved Symbol INS
Previous Symbol IDDM2, IDDM1
Approved Name insulin
Previous Name insulin-dependent diabetes mellitus 2
Location 11p15.5
Position chr11:2159779-2161341, -1
External Links HGNC: 6081
Entrez Gene: 3630
Ensembl: ENSG00000254647
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
De bruyn, A.,1994 Other variant: INS_PvuII Polymorphism Two-point linkage results excluded close linkage of bipolar illness to each candidate gene, and negative linkage results were obtained with the candidate genes DRD4, TH, TYR, and DRD2 under different genetic and phenotypic conditions Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 74)

GO terms by PBA (count: 3)

GO terms by database search (count: 71)


Gene related KEGG pathways (count: 9)

Gene related BioCarta pathways (count: 4)

Gene related interactors from protein-protein interactions data in HPRD (count: 16)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)


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Region: chr11:2159779..2161341 View in gBrowse
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