Gene Report

Basic Info
Approved Symbol ADRA2A
Previous Symbol ADRA2, ADRA2R
Symbol Alias ADRAR
Approved Name adrenoceptor alpha 2A
Previous Name adrenergic, alpha-2A-, receptor
Name Alias alpha-2AAR subtype C10, " alpha-2A-adrenergic receptor"
Location 10q25.2
Position chr10:111077163-111080907, 1
External Links HGNC: 281
Entrez Gene: 150
Ensembl: ENSG00000150594
UCSC: uc001kzo.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Abou Jamra, R., 2004 Other variant: ADRA2A_-1291C>G We observed no significant differences in transmissions for any of the genetic variants in the three ADRA genes. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 64)

GO terms by PBA (count: 6)

GO terms by database search (count: 58)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 8)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr10:111077163..111080907 View in gBrowse
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