Gene Report

Basic Info
Approved Symbol APOB
Approved Name apolipoprotein B
Previous Name apolipoprotein B (including Ag(x) antigen)
Location 2p24-p23
Position chr2:21001429-21044073, -1
External Links HGNC: 603
Entrez Gene: 338
Ensembl: ENSG00000084674
UCSC: uc002red.3
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Winham S.J., 2014 SNP: rs4665788, rs10198175 In the stratified analysis comparing the subtype of BD cases with BE to healthy controls, we identified biologically plausible genetic associations with SNPs in APOB. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 66)

GO terms by PBA (count: 3)

GO terms by database search (count: 63)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 17)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:21001429..21044073 View in gBrowse
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