Gene Report

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Basic Info

Approved Symbol	SLC25A21
Symbol Alias	ODC1, ODC
Approved Name	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
Previous Name	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
Location	14q13.3
Position	chr14:36678431-37172866, -1
External Links	HGNC: 14411 Entrez Gene: 89874 Ensembl: ENSG00000183032 UCSC: uc001wtz.2
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Cruceanu, C., 2013	Other variant: SLC25A21_Chr14:37147560_C/T	Rare variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0044281	small molecule metabolic process	biological process	TAS	117
GO:0006554	lysine catabolic process	biological process	TAS	1
GO:0055085	transmembrane transport	biological process	IEA	77
GO:0005743	mitochondrial inner membrane	cellular component	TAS	12
GO:0034641	cellular nitrogen compound metabolic process	biological process	TAS	20

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
SLC25A21_Chr14:37147560_C/T	others	Chr14:37147560	1 (0/0/1)

Gene related regions (count: 7)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
14q13.2-21.3	chr14:34800000-50400000	1 (0/1/0)
Chr 14	chr14:0-107043718	2 (0/2/0)
14q12-q22.3	chr14:24100000-57600000	1 (1/0/0)
14q13	chr14:32900000-37400000	1 (0/1/0)
14q13.1-21.1	chr14:32900000-43000000	1 (0/1/0)
14q13.1-q24.1	chr14:32900000-69800000	1 (0/1/0)
14q12-q13	chr14:24100000-37400000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:36678431..37172866 View in gBrowse