Region Report

Basic Info

Region Name	Chr 6
Chromosome Position	chr6:0-170805979
No. of Studies (Positive/Negative/Trend)	3(0/3/0)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D6S273	Linkage analysis: broad model, NPL = -0.999, P-value = 0.85;...... Linkage analysis: broad model, NPL = -0.999, P-value = 0.85; narrow model, NPL = -0.704, P-value = 0.85 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Avramopoulos, D., 2007	D6S262 (BPI, BPII), D6S278 (BPI, restricted)	P-value = 0.025, NPL = 1.97, Dominant Max HLOD = 1.17, Re...... P-value = 0.025, NPL = 1.97, Dominant Max HLOD = 1.17, Recessive Max HLOD = 0.51 in Ashkenazi pedigrees; P-value = 0.06, NPL = 1.57, Dominant Max HLOD = 0.83, Recessive Max HLOD = 0.821 in BPI-restricted pedigrees More...	the absolute value of the resulting scores remained moderate the absolute value of the resulting scores remained moderate	Negative
Badner, J. A.,2002		Meta analysis: Location: 1(138), Single Analysis MSP = 0.09,...... Meta analysis: Location: 1(138), Single Analysis MSP = 0.09, Best Analysis MSP = 0.01 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 97)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PRIM2	primase, DNA, polypeptide 2 (58kDa)	6p12-p11.1	1(0/0/1)
POPDC3	popeye domain containing 3	6q21	1(1/0/0)
PDE10A	phosphodiesterase 10A	6q26	1(0/1/0)
BMP6	bone morphogenetic protein 6	6p24-p23	1(1/0/0)
TAAR6	trace amine associated receptor 6	6q23.1	5(4/1/0)
RCAN2	regulator of calcineurin 2	6p12.3	1(0/1/0)
NT5DC1	5'-nucleotidase domain containing 1	6q22.31	1(1/0/0)
KPNA5	karyopherin alpha 5 (importin alpha 6)	6q22.2	1(1/0/0)
PPARD	peroxisome proliferator-activated receptor delta	6p21.2	1(1/0/0)
TBC1D22B	TBC1 domain family, member 22B	6p21.2	1(0/1/0)
LACE1	lactation elevated 1	6q22.1	1(1/0/0)
ZKSCAN4	zinc finger with KRAB and SCAN domains 4	6p21	1(1/0/0)
SYNE1	spectrin repeat containing, nuclear envelope 1	6q25.2	6(3/2/1)
SEC63	SEC63 homolog (S. cerevisiae)	6q21	1(1/0/0)
SCML4	sex comb on midleg-like 4 (Drosophila)	6q21	1(0/1/0)
DTNBP1	dystrobrevin binding protein 1	6p22.3	8(4/3/1)
SOD2	superoxide dismutase 2, mitochondrial	6q25	2(1/1/0)
TNF	tumor necrosis factor	6p21.3	4(2/2/0)
PRSS35	protease, serine, 35	6q14.2	1(0/0/1)
CAGE1	cancer antigen 1	6p24.3	1(1/0/0)
VIP	vasoactive intestinal peptide	6q24-q27	1(1/0/0)
MCHR2	melanin-concentrating hormone receptor 2	6q16	1(1/0/0)
GCLC	glutamate-cysteine ligase, catalytic subunit	6p12	1(0/1/0)
RNF144B	ring finger protein 144B	6p22.3	1(1/0/0)
FAM184A	family with sequence similarity 184, member A	6q22.31	1(1/0/0)
KIAA1009	centrosomal protein 162kDa	6q14.3	0
HLA-G	major histocompatibility complex, class I, G	6p21.3	1(1/0/0)
TBP	TATA box binding protein	6q27	1(0/1/0)
SYNGAP1	synaptic Ras GTPase activating protein 1	6p21.3	1(0/1/0)
HSPA1A	heat shock 70kDa protein 1A	6p21.3	2(2/0/0)
TAAR8	trace amine associated receptor 8	6q23.2	1(0/1/0)
TULP4	tubby like protein 4	6q25-q26	1(1/0/0)
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	6q25.1	1(0/0/1)
RIOK1	RIO kinase 1	6p24.3	2(1/0/1)
COL11A2	collagen, type XI, alpha 2	6p21.3	1(1/0/0)
BVES	blood vessel epicardial substance	6q21	1(1/0/0)
KHDC1	KH homology domain containing 1	6q13	1(0/1/0)
FYN	FYN proto-oncogene, Src family tyrosine kinase	6q21	1(1/0/0)
RFPL4B	ret finger protein-like 4B	6q21	1(1/0/0)
TCTE1	t-complex-associated-testis-expressed 1	6q21.1	1(1/0/0)
TMEM217	transmembrane protein 217	6p21.31-p21.2	1(0/0/1)
ZSCAN31	zinc finger and SCAN domain containing 31	6p	1(1/0/0)
FIG4	FIG4 phosphoinositide 5-phosphatase	6q21	1(1/0/0)
MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6p21	1(1/0/0)
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled	6q14-q15	1(0/1/0)
PSMG4	proteasome (prosome, macropain) assembly chaperone 4	6p25.2	1(0/1/0)
MIR2113	microRNA 2113	6	1(1/0/0)
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9	6p21.3	1(1/0/0)
KIF13A	kinesin family member 13A	6p23	2(0/1/1)
ESR1	estrogen receptor 1	6q24-q27	1(0/1/0)
TIAM2	T-cell lymphoma invasion and metastasis 2	6q25	1(1/0/0)
ARHGAP18	Rho GTPase activating protein 18	6q23.1	1(1/0/0)
CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6p22.3	1(0/1/0)
HCRTR2	hypocretin (orexin) receptor 2	6p12.1	1(1/0/0)
DPCR1	diffuse panbronchiolitis critical region 1	6p21.32	1(0/0/1)
HLA-B	major histocompatibility complex, class I, B	6p21.3	2(0/1/1)
PREP	prolyl endopeptidase	6q22	2(2/0/0)
IMPG1	interphotoreceptor matrix proteoglycan 1	6q14.2-q15	1(0/1/0)
SERINC1	serine incorporator 1	6q22.32	1(1/0/0)
TMEM151B	transmembrane protein 151B	6p21.1	1(1/0/0)
TRIM26	tripartite motif containing 26	6p21.3	2(2/0/0)
ATXN1	ataxin 1	6p23	2(1/1/0)
SLC22A23	solute carrier family 22, member 23	6p25.2	1(1/0/0)
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	6p21.1	1(1/0/0)
NOTCH4	notch 4	6p21.3	2(0/2/0)
SLC17A3	solute carrier family 17 (organic anion transporter), member 3	6p22.2	1(1/0/0)
FKBP5	FK506 binding protein 5	6p21.31	5(1/4/0)
HLA-A	major histocompatibility complex, class I, A	6p21.3	1(0/1/0)
TSPYL4	TSPY-like 4	6q22.1	1(1/0/0)
CEP85L	centrosomal protein 85kDa-like	6q22.31	1(1/0/0)
CEP162	centrosomal protein 162kDa	6q14.3	1(0/0/1)
NR2E1	nuclear receptor subfamily 2, group E, member 1	6q21	1(1/0/0)
GRIK2	glutamate receptor, ionotropic, kainate 2	6q16.3	3(1/1/1)
HSF2	heat shock transcription factor 2	6q22	1(1/0/0)
GRM4	glutamate receptor, metabotropic 4	6p21.3	2(2/0/0)
DST	dystonin	6p12.1	1(0/0/1)
CNR1	cannabinoid receptor 1 (brain)	6q14-q15	5(0/5/0)
QKI	QKI, KH domain containing, RNA binding	6q26	1(0/1/0)
GPX6	glutathione peroxidase 6	6p22.1	1(1/0/0)
DSP	desmoplakin	6p24.3	1(0/0/1)
DDO	D-aspartate oxidase	6q22.1	1(1/0/0)
FABP7	fatty acid binding protein 7, brain	6q22-q23	1(1/0/0)
POU3F2	POU class 3 homeobox 2	6q16.2	1(1/0/0)
FAM26F	family with sequence similarity 26, member F	6q22.1	1(1/0/0)
RGS17	regulator of G-protein signaling 17	6q25.2	1(1/0/0)
HLA-F-AS1	HLA-F antisense RNA 1	6p22.1	1(1/0/0)
ARID1B	AT rich interactive domain 1B (SWI1-like)	6q25.3	1(0/0/1)
SLC22A16	solute carrier family 22 (organic cation/carnitine transporter), member 16	6q21	1(1/0/0)
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	6p12	1(0/1/0)
FOXO3	forkhead box O3	6q21	1(1/0/0)
TAAR1	trace amine associated receptor 1	6q23.1	1(0/1/0)
GUCA1A	guanylate cyclase activator 1A (retina)	6p21.1	2(0/1/1)
PARK2	parkin RBR E3 ubiquitin protein ligase	6q25.2-q27	1(1/0/0)
PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta	6q21-q22.1	1(1/0/0)
GJA1	gap junction protein, alpha 1, 43kDa	6q22.31	1(1/0/0)
GABRR1	gamma-aminobutyric acid (GABA) A receptor, rho 1	6q15	1(1/0/0)
TAAR4P	trace amine associated receptor 4, pseudogene	6q23.2	1(1/0/0)

View in gBrowse

Region: chr6:0..170805979 View in gBrowse