Gene Report

Basic Info
Approved Symbol GUCA1A
Previous Symbol GUCA, GUCA1, C6orf131
Symbol Alias GCAP, GCAP1, COD3, dJ139D8.6, CORD14
Approved Name guanylate cyclase activator 1A (retina)
Previous Name chromosome 6 open reading frame 131
Name Alias cone dystrophy 3
Location 6p21.1
Position chr6:42155406-42180056, 1
External Links HGNC: 4678
Entrez Gene: 2978
Ensembl: ENSG00000048545
UCSC: uc003orx.3
No. of Studies 2 (Positive: 0; Negative: 1; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Georgi, B., 2014 SNP: rs200275941 Amish-specific putative damaging exonic missense variant was found within this gene. Trend Comment on Study
Xu, W., 2014 SNP: rs2492922 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 11)

GO terms by PBA (count: 2)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 5)

Literature-origin SNPs (count: 2)

LD-proxies (count: 3)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:42155406..42180056 View in gBrowse
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