Gene Report

Basic Info
Approved Symbol DDO
Approved Name D-aspartate oxidase
Location 6q22.1
Position chr6:110391771-110415562, -1
External Links HGNC: 2727
Entrez Gene: 8528
Ensembl: ENSG00000203797
UCSC: uc003puc.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fan, J., 2010 SNP: rs3823447, rs6938431 For gene-based test, P-value = 0.00079 in STEP1; P-value = 0.46 in NIMH; P-value = 0.0033 in STEP1 and NIMH. leading gene-based results, but not survive Bonferroni correction test. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 2)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 2)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr6:110391771..110415562 View in gBrowse
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