Gene Report

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Basic Info

Approved Symbol	FAM26F
Previous Symbol	C6orf187
Symbol Alias	RP1-93H18.5, OTTHUMP00000017061, OTTHUMP00000017062, dJ93H18.5
Approved Name	family with sequence similarity 26, member F
Previous Name	chromosome 6 open reading frame 187
Location	6q22.1
Position	chr6:116461370-116463779, 1
External Links	HGNC: 33391 Entrez Gene: 441168 Ensembl: ENSG00000188820 UCSC: uc003pwv.4
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Fan, J., 2010		For gene-based test, P-value = 0.038 in STEP1. nominally significant in STEP1 sample, but not survive Bonferroni correction test.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0006812	cation transport	biological process	IBA	8
GO:0005261	cation channel activity	molecular function	IBA	1
GO:0005887	integral component of plasma membrane	cellular component	IBA	158

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0098655	cation transmembrane transport	biological process	IBA	16
GO:0034220	ion transmembrane transport	biological process	IBA	50

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 6	chr6:0-170805979	3 (0/3/0)
6q14-22	chr6:75200000-130000000	1 (0/0/1)
6q22.1-6q22.33	chr6:114200000-130000000	1 (0/1/0)
6q21-22	chr6:105000000-130000000	1 (0/0/1)
6q22	chr6:114200000-130000000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr6:116461370..116463779 View in gBrowse