Gene Report

Basic Info
Approved Symbol SYNGAP1
Symbol Alias SYNGAP, RASA5, KIAA1938
Approved Name synaptic Ras GTPase activating protein 1
Previous Name synaptic Ras GTPase activating protein 1 homolog (rat)
Location 6p21.3
Position chr6:33419661-33457541, 1
External Links HGNC: 11497
Entrez Gene: 8831
Ensembl: ENSG00000197283
UCSC: uc011dri.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 1 SNP typed, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA.. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 0)

GO terms by database search (count: 18)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 13)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr6:33419661..33457541 View in gBrowse
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