Gene Report

Basic Info
Approved Symbol PDE10A
Approved Name phosphodiesterase 10A
Location 6q26
Position chr6:165327287-165986603, -1
External Links HGNC: 8772
Entrez Gene: 10846
Ensembl: ENSG00000112541
UCSC: uc003quo.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
McDonald, M. L.,2012 SNP: rs10214709, rs1033701, rs1079418, rs2983517, rs2983521, rs3008049, rs4709082, rs470922, rs9365899, rs9459417, rs9459464, rs9459465 None of the association tests of the tagSNPs with either BPD I or BPD II reached genome-wide significance (P < 5E-08). Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 2)

GO terms by database search (count: 11)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 23)

Literature-origin SNPs (count: 12)

LD-proxies (count: 11)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:165327287..165986603 View in gBrowse
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