Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	KIAA1009
Previous Symbol	C6orf84, KIAA1009
Symbol Alias	QN1
Approved Name	centrosomal protein 162kDa
Previous Name	chromosome 6 open reading frame 84, "KIAA1009"
Location	6q14.3
Position	chr6:84124241-84227635, -1
External Links	HGNC: 21107 Entrez Gene: 22832 Ensembl: ENSG00000135315
No. of Studies	0 (Positive: 0; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 0)

Gene functional annotation

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005654	nucleoplasm	cellular component	IDA	163
GO:0005819	spindle	cellular component	IEA	9
GO:0005829	cytosol	cellular component	TAS	223
GO:0005737	cytoplasm	cellular component	IDA	322
GO:0005515	protein binding	molecular function	IPI[23644468]	563
GO:0006996	organelle organization	biological process	TAS	23
GO:0005813	centrosome	cellular component	IDA	34
GO:0042384	cilium assembly	biological process	IMP[23644468]	7
GO:0005814	centriole	cellular component	IDA[23644468]	6
GO:0005879	axonemal microtubule	cellular component	IDA[23644468]	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
KIAA1009	CPNE4	NO	in vitro;yeast 2-hybrid	12522145

Related other genetic factors

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs147915749	chr6:84215348 - 84215348(1)	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1(0/0/1)
rs17790493	chr6:84194886 - 84194886(1)	missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; splice_region_variant	1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 6	chr6:0-170805979	3 (0/3/0)
6q14-22	chr6:75200000-130000000	1 (0/0/1)
6q14	chr6:75200000-87300000	1 (0/0/1)
6q13-q14	chr6:69200000-87300000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr6:84124241..84227635 View in gBrowse