Gene Report

Basic Info
Approved Symbol GABRR1
Approved Name gamma-aminobutyric acid (GABA) A receptor, rho 1
Previous Name gamma-aminobutyric acid (GABA) receptor, rho 1
Name Alias GABA(A) receptor, rho 1
Location 6q15
Position chr6:89177501-89231278, -1
External Links HGNC: 4090
Entrez Gene: 2569
Ensembl: ENSG00000146276
UCSC: uc003pna.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Green, E. K.,2010 SNP: rs9451173 We therefore report suggestive evidence for the involvement of a sixth GABAA receptor gene family member, GABRR1, in susceptibility to bipolarmood phenotypemeetingRDCcriteria for SABP. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 14)

GO terms by PBA (count: 6)

GO terms by database search (count: 8)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 9)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr6:89177501..89231278 View in gBrowse
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