Gene Report

Basic Info
Approved Symbol PARK2
Symbol Alias PDJ, AR-JP, parkin
Approved Name parkin RBR E3 ubiquitin protein ligase
Previous Name Parkinson disease (autosomal recessive, juvenile) 2, parkin, "parkinson protein 2, E3 ubiquitin protein ligase (parkin)"
Name Alias E3 ubiquitin ligase
Location 6q25.2-q27
Position chr6:161347420-162727771, -1
External Links HGNC: 8607
Entrez Gene: 5071
Ensembl: ENSG00000185345
UCSC: uc003qtx.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Noor A., 2014 Selected stringent CNV related to this gene is validated by qPCR from BD case data. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 112)

GO terms by PBA (count: 4)

GO terms by database search (count: 108)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 2)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 2)

Gene related interactors from protein-protein interactions data in HPRD (count: 26)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 5)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:161347420..162727771 View in gBrowse
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