Gene Report
Basic Info
Approved Symbol |
HSPA1A
|
Previous Symbol |
HSPA1 |
Symbol Alias |
HSP70-1 |
Approved Name |
heat shock 70kDa protein 1A |
Previous Name |
heat shock 70kD protein 1A |
Location |
6p21.3 |
Position |
chr6:31815464-31817946, 1 |
External Links |
HGNC: 5232
Entrez Gene: 3303
Ensembl: ENSG00000204389
UCSC: uc003nxj.3
|
No. of Studies |
2 (Positive: 2; Negative: 0; trend: 0)
|
Overlap with SZ? |
YES
|
Overlap with MDD? |
YES
|
Gene related studies (count: 2)
Gene functional annotation
Gene related GO terms (count: 58)
Gene related KEGG pathways (count: 2)
KEGG pathways by PBA (count: 1)
KEGG pathways by database search (count: 1)
Gene related BioCarta pathways (count: 3)
BioCarta pathways by PBA (count: 0)
BioCarta pathways by database search (count: 3)
Gene related interactors from protein-protein interactions data in HPRD (count: 55)
Gene |
Interactor |
Interactor in BDgene? |
Experiment Type |
PMID |
HSPA1A |
RAP1A
|
NO
|
in vivo |
15207703
|
HSPA1A |
NQO1
|
YES
|
in vitro |
11821413
|
HSPA1A |
SOX9
|
NO
|
in vitro;in vivo |
11356186
|
HSPA1A |
YWHAB
|
NO
|
in vivo |
15324660
|
HSPA1A |
BAG3
|
NO
|
in vitro;in vivo |
9873016
,
10980614
|
HSPA1A |
FANCC
|
NO
|
in vitro;in vivo |
11500375
,
12397061
|
HSPA1A |
DNAJA3
|
YES
|
in vivo |
11679576
,
14993262
|
HSPA1A |
MOS
|
NO
|
in vitro;in vivo |
10376524
|
HSPA1A |
TOMM70A
|
NO
|
in vivo |
12526792
|
HSPA1A |
MSR1
|
NO
|
in vitro;in vivo |
11785981
|
HSPA1A |
SLC5A1
|
YES
|
in vitro |
12082088
|
HSPA1A |
DNAJB1
|
NO
|
in vitro;in vivo |
10593983
|
HSPA1A |
DNAJA2
|
NO
|
in vitro |
10651811
|
HSPA1A |
PEX5
|
NO
|
in vitro |
11415446
|
HSPA1A |
PTMA
|
NO
|
in vitro |
11310559
|
HSPA1A |
HCFC1
|
NO
|
in vitro |
12670868
|
HSPA1A |
APEX1
|
NO
|
in vitro;in vivo |
11133992
,
10629618
|
HSPA1A |
DNAJC3
|
NO
|
in vivo;yeast 2-hybrid |
9920933
|
HSPA1A |
AIFM1
|
NO
|
in vitro;in vivo |
11533664
,
12930708
|
HSPA1A |
STUB1
|
NO
|
in vitro;in vivo;yeast 2-hybrid |
10330192
,
15189447
|
HSPA1A |
SNRK
|
NO
|
in vitro;in vivo |
16306228
|
HSPA1A |
PTGES3
|
NO
|
in vivo |
12077419
|
HSPA1A |
GRIN1
|
YES
|
in vivo |
10862698
|
HSPA1A |
DNAJB11
|
NO
|
in vitro |
11584023
|
HSPA1A |
GRIN2D
|
YES
|
in vivo |
10862698
|
HSPA1A |
TP53
|
NO
|
in vivo |
7811761
|
HSPA1A |
TSSK6
|
YES
|
in vivo |
15870294
|
HSPA1A |
IKBKG
|
NO
|
in vivo |
11877453
|
HSPA1A |
EIF2AK2
|
NO
|
in vivo |
12397061
|
HSPA1A |
PRKCA
|
NO
|
in vitro;in vivo |
12080070
|
HSPA1A |
HSBP1
|
NO
|
in vitro;in vivo |
9649501
|
HSPA1A |
WDR16
|
NO
|
in vivo |
15967112
|
HSPA1A |
BAG1
|
NO
|
in vitro;in vivo |
11101523
,
9305631
,
11741305
|
HSPA1A |
RHOA
|
NO
|
in vivo |
12490434
|
HSPA1A |
APAF1
|
NO
|
in vivo |
10934467
|
HSPA1A |
BRSK1
|
NO
|
in vitro;in vivo |
16306228
|
HSPA1A |
YWHAZ
|
NO
|
in vivo |
15324660
|
HSPA1A |
TCERG1
|
NO
|
in vitro |
15456888
|
HSPA1A |
BAG2
|
NO
|
in vitro;in vivo;yeast 2-hybrid |
9873016
|
HSPA1A |
HSPA8
|
NO
|
in vitro |
9305631
,
11741305
|
HSPA1A |
HSF1
|
NO
|
in vitro |
1628823
,
9699716
|
HSPA1A |
STIP1
|
NO
|
in vitro;in vivo |
12161444
,
10786835
|
HSPA1A |
YWHAG
|
NO
|
in vivo |
15324660
|
HSPA1A |
KRT7
|
NO
|
in vivo |
11888936
|
HSPA1A |
YWHAQ
|
YES
|
in vivo |
15324660
|
HSPA1A |
MAP3K5
|
NO
|
in vitro;in vivo |
12391142
|
HSPA1A |
HSPBP1
|
NO
|
in vitro;yeast 2-hybrid |
9830037
|
HSPA1A |
PPP1R15A
|
NO
|
in vivo |
12724406
|
HSPA1A |
ST13
|
YES
|
in vivo |
8887650
|
HSPA1A |
CDK9
|
NO
|
in vitro;in vivo |
10617616
|
HSPA1A |
KRT18
|
NO
|
in vitro |
7529764
|
HSPA1A |
TTC1
|
NO
|
in vitro |
14503850
|
HSPA1A |
BAG4
|
NO
|
in vitro;in vivo |
11527400
,
11909948
|
HSPA1A |
TRIAP1
|
NO
|
in vitro;in vivo |
15735003
|
HSPA1A |
DYX1C1
|
NO
|
in vivo |
15189447
|
Related other genetic factors
Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
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