Gene Report

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Basic Info

Approved Symbol	TMEM217
Previous Symbol	C6orf128
Symbol Alias	dJ355M6.2
Approved Name	transmembrane protein 217
Previous Name	chromosome 6 open reading frame 128
Location	6p21.31-p21.2
Position	chr6:37212180-37258155, -1
External Links	HGNC: 21238 Entrez Gene: 221468 Ensembl: ENSG00000172738 UCSC: uc010jws.4
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Goes, F. S.,2012	SNP: rs1680005	OR = 1.18,P-value(Meta) = 0.00000745 Suggestive association was found.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 6)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs1680005	chr6:37206969 - 37206969(1)		1(0/0/1)

rs_ID	Location	Functional Annotation
rs7753853	chr6:37243253 - 37243253(1)	intron_variant; non_coding_transcript_variant
rs9918399	chr6:37241509 - 37241509(1)	intron_variant; non_coding_transcript_variant
rs1150788	chr6:37211010 - 37211010(1)	downstream_gene_variant
rs1150789	chr6:37212579 - 37212579(1)	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant
rs11970265	chr6:37257365 - 37257365(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 6	chr6:0-170805979	3 (0/3/0)
6p21	chr6:30500000-46200000	1 (0/1/0)
6p21.2	chr6:36600000-40500000	1 (0/1/0)
6p23-p21.1	chr6:13400000-46200000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr6:37212180..37258155 View in gBrowse