Gene Report

Basic Info
Approved Symbol TFAP2B
Symbol Alias AP2-B
Approved Name transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Previous Name transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)
Location 6p12
Position chr6:50818723-50847613, 1
External Links HGNC: 11743
Entrez Gene: 7021
Ensembl: ENSG00000008196
UCSC: uc003pag.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 4 SNP typed, Median D'=1, Median r<sup>2</sup> =0.12, 1 LD blocks, 0.77 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA... This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 60)

GO terms by PBA (count: 5)

GO terms by database search (count: 55)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 7)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

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Region: chr6:50818723..50847613 View in gBrowse
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