BDgene

Gene Report

Basic Info
Approved Symbol ARHGAP18
Symbol Alias MacGAP, bA307O14.2
Approved Name Rho GTPase activating protein 18
Location 6q23.1
Position chr6:129576132-129710225, -1
External Links HGNC: 21035
Entrez Gene: 93663
Ensembl: ENSG00000146376
UCSC: uc003qbr.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0010. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 5)

GO terms by PBA (count: 0)

GO terms by database search (count: 5)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

View in gBrowse

Region: chr6:129576132..129710225 View in gBrowse
View in gBrowse